Bubble-Assisted Sample Preparation Techniques for Mass Spectrometry [0.03%]
微流控气泡辅助样品处理技术在质谱分析中的应用进展研究
Decibel P Elpa,Pawel L Urban
Decibel P Elpa
This review delves into the efficacy of utilizing bubbles to extract analytes into the gas phase, offering a faster and greener alternative to traditional sample preparation methods for mass spectrometry. Generating numerous bubbles in liqu...
A N Verenchikov,V V Makarov,A V Vorobyev et al.
A N Verenchikov et al.
Time-of-flight mass spectrometry (TOF MS) excels in rapid and high-sensitivity analysis, making it a cornerstone of analytical chemistry. But as sample complexity explodes in omics studies, so does the need for higher resolving power to ens...
Sofian Al Shboul,Ashita Singh,Renata Kobetic et al.
Sofian Al Shboul et al.
Some cancers such as glioblastoma (GBM), show minimal response to medical interventions, often only capable of mitigating tumor growth or alleviating symptoms. High metabolic activity in the tumor microenvironment marked by immune responses...
Ion Chemistry in Dielectric Barrier Discharge Ionization: Recent Advances in Direct Gas Phase Analyses [0.03%]
介质阻挡放电离子化的离子化学：直接气相分析的最新进展
Kseniya Dryahina,Miroslav Polášek,Juraj Jašík et al.
Kseniya Dryahina et al.
Dielectric barrier discharge ionization (DBDI) sources, employing low-temperature plasma, have emerged as sensitive and efficient ionization tools with various atmospheric pressure ionization processes. In this review, we summarize a histor...
Mass Spectrometry-Based Proteomics for Assessing Epitranscriptomic Regulations [0.03%]
基于质谱的蛋白质组学在表转录组调控研究中的应用
Yen-Yu Yang,Zhongwen Cao,Yinsheng Wang
Yen-Yu Yang
Epitranscriptomics is a rapidly evolving field that explores chemical modifications in RNA and how they contribute to dynamic and reversible regulations of gene expression. These modifications, for example, N6-methyladenosine (m6A), are cru...
Ion Source Complementarity for Characterization of Complex Organic Mixtures Using Fourier Transform Mass Spectrometry: A Review [0.03%]
傅里叶变换质量 spectrometry表征复杂有机混合物的离子源互补性评论文章
Charlotte Mase,Maxime Sueur,Hélène Lavanant et al.
Charlotte Mase et al.
Complex organic mixtures are found in many areas of research, such as energy, environment, health, planetology, and cultural heritage, to name but a few. However, due to their complex chemical composition, which holds an extensive potential...
Mass Spectrometry Analysis of Nucleic Acid Modifications: From Beginning to Future [0.03%]
核酸修饰的质谱分析：从过去到现在及未来展望
Yixuan Xie,Carolina Brás-Costa,Zongtao Lin et al.
Yixuan Xie et al.
Nucleic acids are fundamental biological molecules that encode and convey genetic information within living organisms. Over 150 modifications have been found in nucleic acids, which are involved in critical biological functions, including r...
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross-Linking [0.03%]
基于有限蛋白酶解和交联的质谱结构蛋白质组学
Haiyan Lu,Zexin Zhu,Lauren Fields et al.
Haiyan Lu et al.
The exploration of protein structure and function stands at the forefront of life science and represents an ever-expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at...
Yang Cai
Yang Cai
Primary amines, in the form of unmodified N-terminus of peptide/protein and unmodified lysine residue, are perhaps the most important functional groups that can serve as the starting points in proteomic analysis, especially via mass spectro...
Origin and characterization of cyclodepsipeptides: Comprehensive structural approaches with focus on mass spectrometry analysis of alkali-cationized molecular species [0.03%]
环肽 depsipeptides 的起源与结构特征研究：以碱金属离子化分子物种质谱分析为重点的系统性结构方法研究
Sophie Liuu,Annelaure Damont,Alain Perret et al.
Sophie Liuu et al.
Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide-related natural products made up of both proteinogenic and nonprotein...