An update on multiplexed mass spectrometry-based lysosomal storage disease diagnosis [0.03%]
基于多重质谱的溶酶体贮积症诊断的最新进展
Laura Darie-Ion,Brînduşa Alina Petre
Laura Darie-Ion
Lysosomal storage disorders (LSDs) are a type of inherited metabolic disorders in which biomolecules, accumulate as a specific substrate in lysosomes due to specific individual enzyme deficiencies. Despite the fact that LSDs are incurable, ...
Xiaoping Zhang,Vladimir Frankevich,Jianhua Ding et al.
Xiaoping Zhang et al.
The molecular composition of exhaled human breath can reflect various physiological and pathological conditions. Considerable progress has been achieved over the past decade in real-time analysis of exhaled human breath using direct mass sp...
Rafael Stroggilos,Aggeliki Tserga,Jerome Zoidakis et al.
Rafael Stroggilos et al.
We are approaching the third decade since the establishment of the very first proteomics repositories back in the mid-'00s. New experimental approaches and technologies continuously enrich the field while producing vast amounts of mass spec...
Microstructure characterization and mechanistic insight into polyether polyols and their associated polyurethanes [0.03%]
聚醚多元醇及其相关聚氨酯的显微结构表征及机理研究
Anthony P Gies,David M Hercules,Arjun Raghuraman et al.
Anthony P Gies et al.
This article reviews the analytical tool chest used for characterizing alkoxylates and their associated copolymer mixtures. Specific emphasis will be placed upon the use of mass spectrometry-based techniques as rapid characterization tools ...
Eva M Del Amo,Kati-Sisko Vellonen,Arto Urtti et al.
Eva M Del Amo et al.
Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and ...
Maria Khalikova,Jakub Jireš,Ondřej Horáček et al.
Maria Khalikova et al.
The role of mass spectrometry (MS) has become more important in most application domains in recent years. Pharmaceutical analysis is specific due to its stringent regulation procedures, the need for good laboratory/manufacturing practices, ...
A tutorial: Laserspray ionization and related laser-based ionization methods for use in mass spectrometry [0.03%]
激光喷涂离子化及相关基于激光的电离方法在质谱仪中的应用教程
Sarah Trimpin
Sarah Trimpin
This Tutorial is to provide a summary of parameters useful for successful outcomes of laserspray ionization (LSI) and related methods that employ a laser to ablate a matrix:analyte sample to produce highly charged ions. In these methods the...
Karel Lemr,Vladimír Havlíček
Karel Lemr
Recent advances in mass spectrometry techniques for atmospheric chemistry research on molecular-level [0.03%]
分子尺度大气化学研究中质谱技术的最新进展
Wen Zhang,Lu Xu,Haofei Zhang
Wen Zhang
The Earth's atmosphere is composed of an enormous variety of chemical species associated with trace gases and aerosol particles whose composition and chemistry have critical impacts on the Earth's climate, air quality, and human health. Mas...
Guilherme J Guimaraes,Jaeah Kim,Michael G Bartlett
Guilherme J Guimaraes
Therapeutic messenger RNAs (mRNAs) have emerged as powerful tools in the treatment of complex diseases, especially for conditions that lack efficacious treatment. The successful application of this modality can be attributed to its ability ...