Restoration, Not Bypass: Otoferlin Gene Therapy and a New Era in Hearing Loss Treatment [0.03%]
治愈,不要绕过:Otoferlin基因治疗和听力损失治疗新时代
Jazlyn A Selvasingh,Justin R Shinn
Jazlyn A Selvasingh
The FDA approval of Otarmeni, an AAV-based gene therapy for biallelic OTOF-associated sensorineural hearing loss, represents a conceptual shift in otology: from bypassing defective auditory physiology to restoring it. Unlike cochlear implan...
Implementation of a Nebulized Tranexamic Acid Protocol for Pediatric Post-Tonsillectomy Hemorrhage: A Quality Improvement Initiative [0.03%]
儿童扁桃体术后出血的雾化氨甲环酸治疗方案的实施:一项质量改进倡议
Kyle W Singerman,Andrea Nguyen,Blake Welker et al.
Kyle W Singerman et al.
Objective: We hypothesized that initiation of a standardized nebulized TXA protocol for posttonsillectomy hemorrhage (PTH) would reduce the need for surgical control of bleeding without increasing adverse clinical outcome...
Characterizing Music Engagement and Reward in Individuals Across a Spectrum of Hearing Loss and Rehabilitation [0.03%]
听觉损伤和康复人群的音乐参与及奖赏机制研究
Emily Gao,Maria Armache,Joon Soo Kim et al.
Emily Gao et al.
Objective: Hearing aids (HAs) and cochlear implants (CIs) improve speech perception for individuals with hearing loss (HL), yet their impact on music outcomes remains unclear. We examined music perception, engagement, and...
Airway Risk in Angioedema: Validation of a Clinical Triage Algorithm for ENT Referral [0.03%]
耳鼻喉转诊的血管性水肿气道风险临床分诊算法验证研究
Dan Yaniv,Igor Vainer,Dean Dudkiewicz et al.
Dan Yaniv et al.
Objective: To identify clinical factors associated with laryngeal involvement in patients with angioedema and to validate a triage algorithm for determining the need for nasopharyngoscopic evaluation in the emergency depa...
Toward a Functional Terminology: Reconsidering "Minor Laryngeal Clefts" as Interarytenoid Dysfunction [0.03%]
迈向功能术语学:重新审视“喉小裂”作为室间隔功能障碍
Colin Smith,Nancy M Bauman,Hengameh K Behzadpour et al.
Colin Smith et al.
Much confusion surrounds the terminology used to describe minor laryngeal clefts in pediatric otolaryngology. The widely accepted Benjamin-Inglis classification defined type 1 clefts as those where the interarytenoid mucosal is at the level...
Development of Novel mRNA Classifiers to Stratify Preoperative Thyroid Tumor Risk [0.03%]
开发新的mRNA分类器以分层评估术前甲状腺肿瘤风险
Thomas F Barrett,Mohamed Jama,Mohammed Alshalalfa et al.
Thomas F Barrett et al.
Objective: Develop a preoperative risk classifier for guiding the extent of surgery in differentiated thyroid carcinomas (DTCs) under 4 cm. Study design: ...
Real-Time Light-Guided Vocal Fold Injection for Unilateral Vocal Fold Paralysis: Experience From 378 Consecutive Cases [0.03%]
单侧声带麻痹的实时导光声带内注射:连续378例的经验总结
Seo Young Kim,Jeong-Yeon Ji,Woo-Jin Jeong et al.
Seo Young Kim et al.
Objective: Accurate needle localization is a key challenge in the cricothyroid (CT) approach to vocal fold injection (VFI) due to invisibility. Real-time light-guided VFI (RL-VFI) was developed to enhance precision throug...
Preoperatively Diagnosed Versus Undiagnosed Major Salivary Gland Cancer: Clinicopathological Characteristics, Treatment Strategies, and Oncological Outcomes [0.03%]
术前诊断与未诊断的重大唾液腺癌的临床病理特征、治疗策略及肿瘤结局
Dongbin Ahn,Joseph Califano,Jihye Kwak et al.
Dongbin Ahn et al.
Objective: To evaluate differences in clinicopathological characteristics, treatment strategies, and oncological outcomes between preoperatively diagnosed and undiagnosed major salivary gland cancers (MSGCs). ...
Estimating Performance Using Tonotopic Measurements of Intracochlear Electrocochleography: Comparison of Lateral Wall and Perimodiolar Arrays [0.03%]
耳蜗内电反应的 tonotopic 测量估计性能:螺旋花环和周边柱阵列的比较
Jordan J Varghese,Matthew A Shew,Amit Walia et al.
Jordan J Varghese et al.
Objective: To assess intracochlear electrocochleography (ECochG) for estimating cochlear implant (CI) performance for lateral wall and perimodiolar electrode arrays. ...
Head and Neck Free Flap Reconstruction: Current Landscape and Emerging Technologies [0.03%]
头颈部游离皮瓣修复的现状与新兴技术
Sholem Hack,Eric Remer,Eran E Alon et al.
Sholem Hack et al.
Objective: To synthesize contemporary developments in head and neck oncologic free flap reconstruction, with emphasis on perioperative physiologic optimization, digital integration, and functional recovery. ...