Highly selective, allosteric inhibition of TYK2 with oral ESK-001 in patients with moderate-to-severe plaque psoriasis: Results from STRIDE, a 12-week, randomized, double-blinded, placebo-controlled, dose-ranging Phase 2 study [0.03%]
一项为期12周的斑块型银屑病患者II期临床试验(STRIDE)结果:口服ESK-001对中重度斑块型银屑病患者的TYK2高选择性别构抑制作用
Andrew Blauvelt,Petr Arenberger,Maxwell B Sauder et al.
Andrew Blauvelt et al.
Background: ESK-001, a novel allosteric, highly selective oral TYK2 inhibitor in development for treatment of immune-mediated disorders, was well-tolerated, and achieved high levels of target inhibition in Phase 1 studies...
The Prospective Registry Of MyositIS (PROMIS): II. Temporal shifts in causes of death among patients with idiopathic inflammatory myopathies [0.03%]
特发性炎性肌病患者的肌炎前瞻性登记处(PROMIS) :病因死亡率的变化趋势分析
Chen Yu,Chanyuan Wu,Shangyi Jin et al.
Chen Yu et al.
Background: Idiopathic inflammatory myopathies (IIM) are heterogeneous autoimmune diseases with variable long-term outcomes. Objective: ...
Correction [0.03%]
改正通知书
Is Ignorance Bliss? Ethical Implications of Parental Refusal of Biopsies in Pediatric Patients [0.03%]
不知为福?——父母拒绝为儿科病人进行活检的伦理意义
Timothy Klufas,Simran Saini,Albert E Zhou et al.
Timothy Klufas et al.
A Retrospective Cohort Study Evaluating the Impact of Tranexamic Acid on Melanoma Risk [0.03%]
评价氨甲环酸对 melanoma 风险影响的队列研究
Madelyn Schmidt,Marie Vu,Smiti Gandhi et al.
Madelyn Schmidt et al.
Melanoma Rates After In Vitro Fertilization Treatment: a TriNetX Study [0.03%]
体外受精治疗后的黑色素瘤发病率:一项TriNetX研究
Amit Singal,Jennifer A Stein,Shari R Lipner
Amit Singal
Ayushya Ajmani,Albert E Zhou,Jane M Grant-Kels et al.
Ayushya Ajmani et al.
Oral tofacitinib in comparison with dexamethasone oral mini-pulse therapy for the treatment of active nonsegmental vitiligo: A randomized controlled trial [0.03%]
托法替尼口服治疗与地塞米松小剂量脉冲疗法对比治疗白癜风的疗效:一项随机对照试验
Anubha Dev,Keshavamurthy Vinay,Anuradha Bishnoi et al.
Anubha Dev et al.
Background: There is a lack of literature on stabilizing and repigmenting potential of oral tofacitinib in active vitiligo. Objective: ...
Patient-reported Psychosocial Impact of Alopecia Areata in China: A Multicenter Cross-Sectional Study [0.03%]
中国斑秃患者的报告的心理社会影响:一项多中心横断面研究
Xiangqian Li,Xufeng Du,Hengguang Zhao et al.
Xiangqian Li et al.