Heteronuclear Two-Dimensional NMR for Quantification of Candesartan Cilexetil [0.03%]
用于定量坎地沙坦酯的异核二维NMR法
Veera Reddy Pinninti,C H Krishnam Raju,Arunima Pola et al.
Veera Reddy Pinninti et al.
One-dimensional quantitative NMR (qNMR) has been predominantly applied to accurately quantify pharmaceutical compounds. However, its application to complex molecules is limited due to several challenges, such as signal response overlap and ...
Tutorial: Saturation Transfer Difference NMR for Studying Small Molecules Interacting With Nanoparticles [0.03%]
饱和转移差异核磁共振研究纳米颗粒与小分子相互作用的原理及应用——教程
Sekinah O Dauda,Rajan Rai,Stephanie P Palma et al.
Sekinah O Dauda et al.
Saturation transfer difference (STD) NMR is a robust, versatile technique for detecting small molecules binding to large receptors. In addition to identifying binding molecules in the presence of nonbinding molecules, the STD-NMR technique ...
Spectral Density Function Analysis Reveals Coupled Relaxation and Resonance Modes in Fluorinated Elastomers: Comparison With Semicrystalline Poly(tetrafluoroethylene) [0.03%]
光谱密度函数分析揭示了氟化弹性体中的松弛和共振模式的相互作用：与半结晶聚四氟乙烯比较研究
Natsuki Kawabata,Naoki Asakawa,Teruo Kanki
Natsuki Kawabata
We reveal contrasting behaviors in molecular motion between the two materials, including the identification of resonance-enhanced dynamic features in elastomers. We present a depth-resolved analysis of molecular dynamics in semicrystalline ...
Determination of Ethoxy Content in Ethylcellulose via Relative Quantitative 1H NMR Spectroscopy [0.03%]
相对定量氢-1核磁共振光谱法测定乙基纤维素中乙氧基含量
Xiaoyan Zhang,Yaozuo Yuan,Yang Liu et al.
Xiaoyan Zhang et al.
The research team established a quantitative 1H NMR method to determine the relative ethoxy content (EO%) in ethylcellulose using a CDCl3/TFA-d solvent mixture. High-field NMR spectroscopy enabled direct measurement without the use of inter...
Pooja Kumari,Priya Yadav,Neel Sarovar Bhavesh
Pooja Kumari
Epithelial splicing regulatory protein 2 (ESRP2) plays a pivotal role in alternative splicing regulation, particularly in maintaining epithelial cell identity and suppressing epithelial-to-mesenchymal transition (EMT). Despite its biologica...
Lars T Kuhn,Míriam Pérez-Trujillo
Lars T Kuhn
Photo-chemically induced dynamic nuclear polarisation (photo-CIDNP) is a nuclear spin-selective magnetic resonance phenomenon that has traditionally been used to mechanistically study chemical reactions involving the (transient) formation o...
A Longitudinal NMR-Based Metabolomics Highlights Shared Mechanisms of Pathophysiology in ARDS Patients With and Without Sepsis [0.03%]
基于纵向核磁共振代谢组学高光ARDS患者共同的病理生理机制（无论其是否伴有脓毒症）
Anamika Singh,Mohd Adnan Siddiqui,Afzal Azim et al.
Anamika Singh et al.
Acute respiratory distress syndrome (ARDS) is a life-threatening condition often complicated by sepsis, leading to worse clinical outcomes. The role of biomarkers in distinguishing ARDS with and without sepsis remains unclear. This study ai...
Structure Elucidation and Complete NMR Spectral Assignments of New Sesquiterpenes Isolated From Marine Derived Fungus Aspergillus sydowii-HB [0.03%]
来源于海洋来源曲霉菌的新倍半萜的结构鉴定及完整的NMR谱解析
Baorui Teng,Sijing Liu,Dan Zhang et al.
Baorui Teng et al.
Six sesquiterpene derivative compounds (1-6), including one new 7R-sydowic acid (1) and five known compounds (2-6) were isolated from the secondary metabolites of Aspergillus sydowii-HB. The structures were determined by NMR spectroscopy an...
NMR Approaches to Study Drug-Surfactant Interactions: Insights From NOE, Relaxometry and Diffusometry [0.03%]
用于研究药物与表面活性剂相互作用的核磁方法：NOE、松弛和扩散测定的新见解
B V N Phani Kumar
B V N Phani Kumar
Characterising drug-binding mechanisms, structural changes and dynamics at atomic resolution remains a challenge due to the dynamic and heterogeneous nature of surfactant supramolecular assemblies. In this context, nuclear magnetic resonanc...
Arpita Prasad,Zofishan Iqra Anjum,Ashutosh Kumar
Arpita Prasad
G-protein-coupled receptors (GPCRs) are the largest and most heterogeneous group of cell membrane receptors dictating various physiological processes. GPCRs are the pivotal points for orchestrating almost every cellular response, making the...