Posthemorrhagic hydrocephalus development after germinal matrix hemorrhage: Established mechanisms and proposed pathways [0.03%]
早产儿脑室周围-室内出血后脑积水发病机制及防治措施研究进展
Damon Klebe,Devin McBride,Paul R Krafft et al.
Damon Klebe et al.
In addition to being the leading cause of morbidity and mortality in premature infants, germinal matrix hemorrhage (GMH) is also the leading cause of acquired infantile hydrocephalus. The pathophysiology of posthemorrhagic hydrocephalus (PH...
Pre-injury monocyte/macrophage depletion results in increased blood-brain barrier permeability after traumatic brain injury [0.03%]
伤前单核细胞/巨噬细胞耗竭增加创伤性脑损伤后的血脑屏障通透性
Benjamin M Aertker,Akshita Kumar,Karthik S Prabhakara et al.
Benjamin M Aertker et al.
Traumatic brain injury (TBI) effects both the brain and the immune system. Circulating monocytes/macrophages (Mo /Ma ) after a TBI may play an important role in preserving the blood-brain barrier (BBB), reducing brain edema, and interacting...
GABA-containing compound gammapyrone protects against brain impairments in Alzheimer's disease model male rats and prevents mitochondrial dysfunction in cell culture [0.03%]
一种含GABA化合物gammapyrone能保护阿尔茨海默病模型雄性大鼠脑损伤并能防止细胞培养中的线粒体功能障碍
Vladimirs Pilipenko,Karina Narbute,Ines Amara et al.
Vladimirs Pilipenko et al.
Neuroinflammation, oxidative stress, decreased glucose/energy metabolism, and disrupted neurotransmission are changes that occur early in sporadic Alzheimer's disease (AD), manifesting as mild cognitive impairment. Recently, the imbalanced ...
Thirty-day readmissions in aneurysmal subarachnoid hemorrhage: A good metric for hospital quality? [0.03%]
动脉瘤性蛛网膜下腔出血30天内再次入院率能体现医院医疗水平吗？
Isaac Ng,Rose Du
Isaac Ng
Thirty-day readmission rates has been increasingly used by clinicians, hospital administrators, and policy makers as a metric for the quality of care. However, the 30-day readmission rates may be affected by other factors intrinsic to the p...
K Duris,M Jurajda
K Duris
The immune system plays an important role under both physiological and pathological conditions. Immune surveillance as well as defense and healing processes are crucial for the organism, but the immune system has a natural tendency to act a...
Anna Wikman,Cathrine Axfors,Stavros I Iliadis et al.
Anna Wikman et al.
Maternal perinatal depression (PND), a common mental disorder with a prevalence of over 10%, is associated with long-term health risks for both mothers and offspring. This study aimed at describing characteristics related to background and ...
Differential impacts on multiple forms of spatial and contextual memory in diazepam binding inhibitor knockout mice [0.03%]
在diazepam结合抑制剂基因敲除小鼠中对多种空间和情境记忆形式的差异影响
Ammar L Ujjainwala,Connor D Courtney,Natalia M Wojnowski et al.
Ammar L Ujjainwala et al.
Learning and memory are fundamental processes that are disrupted in many neurological disorders including Alzheimer's disease and epilepsy. The hippocampus plays an integral role in these functions, and modulation of synaptic transmission m...
Hajime Hirase,Sonam Akther,Xiaowen Wang et al.
Hajime Hirase et al.
The hippocampus is a limbic structure involved in the consolidation of episodic memory. In the recent decade, glycogenolysis in the rodent hippocampus has been shown critical for synaptic plasticity and memory formation. Astrocytes are the ...
Diffusion kurtosis imaging in mild traumatic brain injury and postconcussional syndrome [0.03%]
轻度创伤性脑损伤和脑震荡后的扩散张量及弥散 Kurtosis 研究
Rune Hatlestad Karlsen,Cathrine Einarsen,Hans Kristian Moe et al.
Rune Hatlestad Karlsen et al.
Aims of this study were to investigate white matter (WM) and thalamus microstructure 72 hr and 3 months after mild traumatic brain injury (TBI) with diffusion kurtosis imaging (DKI) and diffusion tensor imaging (DTI), and to relate DKI and ...
Distinct differences in rates of oxygen consumption and ATP synthesis of regionally isolated non-synaptic mouse brain mitochondria [0.03%]
区域性分离的小鼠脑非突触线粒体耗氧率和ATP合成速率的差异性研究
Jens V Andersen,Emil Jakobsen,Helle S Waagepetersen et al.
Jens V Andersen et al.
Brain mitochondrial dysfunction has been implicated in several neurodegenerative diseases. The distribution and efficiency of mitochondria display large heterogeneity throughout the regions of the brain. This may imply that the selective re...