Survival Impact and Risk Factors of Cervical Lymph Node Metastasis in Maxillary Gingival Squamous Cell Carcinoma: A Retrospective Study of 81 Patients [0.03%]
81例上颌牙龈鳞癌淋巴结转移的预后及危险因素分析：一项回顾性研究
Takeshi Kuroshima,Naoya Kinoshita,Naoto Nishii et al.
Takeshi Kuroshima et al.
Background: This study aimed to investigate the survival impact and predictive factors of cervical lymph node metastasis (CLNM) in patients with maxillary gingival squamous cell carcinoma (MGSCC). ...
Abbas M Hassan,Michael M Talanker,Peirong Yu et al.
Abbas M Hassan et al.
Background: An analysis of all possible lip defects and a comparison of outcomes following various reconstructive techniques is lacking in the literature. ...
Tongue Surface Electromyography Detects Reduced Motor Unit Recruitment in Oropharyngeal Cancer Survivors With Hypoglossal Neuropathy [0.03%]
舌面电肌图检测舌下神经病的口咽癌生存者的运动单位募集减少
Nathan J Hansen,Katherine A Hutcheson,Holly McMillan et al.
Nathan J Hansen et al.
Background: This proof-of-concept case-control study examined the feasibility of tongue high-density surface electromyography (HDS-EMG) to detect hypoglossal neuropathy. ...
Postoperative Radiotherapy for Head and Neck Merkel Cell Carcinoma: Sometimes, Less Is More [0.03%]
低剂量放疗与高剂量放疗治疗头颈部默克尔细胞癌的疗效比较研究有时，“少即是多”
Yuan Zheng,Di Zhang,Qihao Sun et al.
Yuan Zheng et al.
Background: Head and neck Merkel cell carcinoma (HNMCC) is a rare but aggressive malignancy characterized by high recurrence rates and an uncertain survival benefit from postoperative radiotherapy (PORT). This study aimed...
Cetuximab Hypersensitivity in the Setting of Asymptomatic Alpha-Gal Sensitization [0.03%]
无临床症状的α-半乳糖苷过敏患者使用西妥昔单抗导致超敏反应病例报告
Alexander G Emerson,Lindsay Mundy,Barbara A Murphy et al.
Alexander G Emerson et al.
Background: Alpha-gal syndrome is an allergic condition resulting from the bite of the Lonestar tick in the southeastern US that leads to sensitization to mammalian products containing the oligosaccharide galactose-alpha-...
Case Reports
Head & neck. 2025 Aug 28. DOI:10.1002/hed.70030 2025
Neck Dissection Reduces Risk of Recurrence in Early-Stage Oral Tongue Cancer [0.03%]
早期舌癌患者进行颈淋巴清扫可降低复发风险
Jaclyn Lee,Tan Ding,Mae Wimbiscus et al.
Jaclyn Lee et al.
Background: Patterns of failure in early-stage oral tongue squamous cell carcinoma (OTSCC) managed with surgery alone remain understudied. Methods: ...
Evaluation of a Novel Prognostic System for Surgically Resected Oral Cavity Carcinoma [0.03%]
新型口咽癌手术后预后系统的评估研究
Alisa Rybkin,Victor Lee,Melissa R Young et al.
Alisa Rybkin et al.
Background: The Oral Cavity Predictive Score (OCCPS) is a point-based system including T/N stage, LVSI, and grade that has been validated for predicting distant metastasis. We tested its ability to predict overall surviva...
Podoplanin Expression and the Risk of Malignant Transformation of Oral Pre-Malignant Disease: A Systematic Review and Meta-Analysis [0.03%]
podoplanin表达与口腔癌前病变恶性转化风险的相关性系统评价和 meta 分析
Erin E Briggs,Nathaniel Schlosser,Shaun A Nguyen et al.
Erin E Briggs et al.
Background: Podoplanin is a mucin-like transmembrane glycoprotein expressed in oral epithelium with a documented role in cell motility, tumorigenesis, tumor invasion, and metastasis. Podoplanin is a potentially valuable b...
Review
Head & neck. 2025 Aug 26. DOI:10.1002/hed.70018 2025
The Importance of Recognition and Management of Oral Lichen Planus: Navigating Epidemiology, Pathogenesis, Cancer Risk, and Advances in Management [0.03%]
口腔扁平苔藓的识别与管理的重要性：探讨流行病学、发病机制、癌症风险及治疗进展
Elahe Akbari,Joel B Epstein,Firoozeh Samim
Elahe Akbari
Background: Oral lichen planus (OLP) is a chronic inflammatory disorder classified as an oral potentially malignant disorder (OPMD) due to its association with an increased prevalence and a risk of progressing to oral squ...
Review
Head & neck. 2025 Aug 25. DOI:10.1002/hed.70012 2025
Safety and Efficacy Findings From a Phase Ib/II Study of ASP-1929 Photoimmunotherapy With Pembrolizumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma [0.03%]
ASP-1929光免疫疗法与派姆单抗治疗复发和/或转移性头颈部鳞癌 Ib/II 期临床研究的安全性和疗效结果
David M Cognetti,Joseph M Curry,Jennifer Johnson et al.
David M Cognetti et al.
Background: ASP-1929 photoimmunotherapy-cetuximab conjugated to IRDye 700DX and red light (690 nm) for localized drug activation-results in rapid, selective cell killing. ...