Genetic Investigation of Fetal Left-Right Laterality Defects Identified in the Second Trimester of Pregnancy [0.03%]
妊娠中期产前检查发现胎儿左右不对称缺陷的遗传学研究分析
Qiu-Xia Yu,Jia-Chun Guo,Yong-Ling Zhang et al.
Qiu-Xia Yu et al.
Objective: To explore genetic investigative results in fetuses with left-right (LR) laterality defects. Methods: This was a retrospecti...
Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions [0.03%]
遗传病患者产前诊断利用情况的横断面研究
Ebunoluwa Ojo,Roni Zemet,Allyson Nevins et al.
Ebunoluwa Ojo et al.
Objective: Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision-making regarding management options. The aim of this study was to assess prenata...
Radial Expansion of Chorioamniotic Membranes After Perforation Causes Less Damage Than Fixed Diameter Instruments [0.03%]
膜穿刺后的放射状扩张造成的损害小于固定直径的器械造成的损害
Selena Shirkin,Alice Yu,Eric McAlexander et al.
Selena Shirkin et al.
Objective: Iatrogenic preterm premature rupture of membranes (iPPROM) complicates up to 40% of fetoscopic surgeries, driven by the limited healing potential of the chorioamniotic membrane after perforation. While radial e...
Reassurance-Focused First-Trimester Euploidy Screening With Machine Learning [0.03%]
基于机器学习的以安慰为导向的早期妊娠非整倍体筛查
Paula Idalia Szenejko,Filip Andrzej Dąbrowski,Szymon Płotka et al.
Paula Idalia Szenejko et al.
Objective: To develop and internally validate a machine-learning (ML) model for first-trimester screening that prioritizes fetal euploidy reassurance and to compare its performance with the conventional Combined Screening...
Evaluating the Utility of RNAseq in Prenatal Diagnostics: Expression Profiles of Cultured Chorionic Villus and Amniotic Fluid Samples [0.03%]
评估RNA测序在产前诊断中的实用性：培养绒毛和羊水样本的表达谱分析
Maria C Vladoiu,Sen Zhao,Roni Zemet et al.
Maria C Vladoiu et al.
Objective: While RNAseq has enhanced variant interpretation in postnatal cases, its potential in the prenatal setting remains underexplored. This study investigates the utility of RNAseq in prenatal diagnostics by analyzi...
Prenatal Diagnosis of Congenital Heart Disease in a Developing Country-A Cross-Sectional Study [0.03%]
发展中国家先天性心脏病产前诊断的现状--一项横断面研究
Lina Hammoud,Rana Zareef,Jad Abdul Khalek et al.
Lina Hammoud et al.
Objective: Prenatal detection of congenital heart disease (CHD) remains suboptimal in resource-limited settings. We quantified prenatal CHD detection, fetal echocardiography utilization, and predictors of counseling for f...
Effects of Maternal Hyperoxygenation on Fetal Hemodynamics Assessed by Ultrasound and Fetal Echocardiography in Congenital Heart Disease: A Systematic Review and Single Arm Meta-Analysis [0.03%]
母体 hyperoxygenation 对先天性心脏病胎儿血流动力学影响的系统评价及单臂 meta 分析：基于超声和胎儿超声心动图评估
Giovanna C C Martin,Maria J Lemos,Ana C P Servidoni et al.
Giovanna C C Martin et al.
Objectives: To evaluate the effects of maternal hyperoxygenation (MH) on fetal hemodynamic parameters assessed by ultrasound and fetal echocardiography in pregnancies complicated by congenital heart disease (CHD). ...
Prenatal Diagnosis of CDK13-Related Disorder Presented With Isolated Polyhydramnios and Micrognathia [0.03%]
以羊水过多和小下颌为表现的CDK13相关障碍的产前诊断
Ru Li,Gui-Lan Chen,Dong-Zhi Li
Ru Li
Case Reports
Prenatal diagnosis. 2026 Apr 6. DOI:10.1002/pd.70148 2026
In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies [0.03%]
宫内HSC移植治疗镰状细胞病：一种克服当前疗法局限性的潜在治疗方法
Oluwaseun O Babatunde,Madeleine G Bibby,Anthony Atala et al.
Oluwaseun O Babatunde et al.
Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene-modified autologous hematopoietic st...
Interventions and Perinatal Outcomes Associated With Recipient Twin Cardiomyopathy in the Setting of Twin-To-Twin Transfusion Syndrome: A Systematic Review [0.03%]
受体孪生子心肌病并发双胞胎输血综合征的干预和围产期结局：系统性回顾
Briana Tolbert,Sandhya Chandrasekaran,Vanya Manthena et al.
Briana Tolbert et al.
Objective: To determine (1) Whether the presence and severity of recipient twin cardiomyopathy in the setting of twin-to-twin transfusion syndrome are associated with worse perinatal outcomes when compared to recipient tw...