Vaishali Mehta,Emily B Rosenfeld,Julia Geltch et al.
Vaishali Mehta et al.
Objective: To evaluate ethnic disparities in carrier status ascertainment between Tier 3 (conditions with carrier frequency ≥ 1/200) and Tier 4 panels (conditions with carrier frequencies < 1/200), and to assess the util...
Enhancing Prenatal Genetic Evaluation Through the Combination of Single-Gene Non-Invasive Prenatal Screening and Prenatal Imaging [0.03%]
Sarah Araji,Jennifer L Cohen
Sarah Araji
Cell free DNA (cfDNA) screening for common aneuploidies is now widely integrated into prenatal care, and recent advances in next-generation sequencing, enhanced by unique molecular indexing methodology, have enabled cfDNA for selected singl...
First-Trimester Molecular Screening for Fetal and Neonatal Alloimmune Thrombocytopenia: Early Identification of At-Risk Pregnancies [0.03%]
Sebastián Blanco,Luis Horacio Carrizo,José María Lazarte et al.
Sebastián Blanco et al.
Objective: The aim of this study was to evaluate the feasibility and clinical value of implementing first-trimester molecular HPA screening to identify pregnancies at risk for FNAIT. ...
Is There Potential Clinical Utility in Reporting Variants of Uncertain Significance From Prenatal Sequencing? [0.03%]
产前测序报告意义不明变异的潜在临床作用有多大？
A Gibbs,R Braham,V Ramachandran et al.
A Gibbs et al.
Objective: Prenatal sequencing of fetuses with abnormalities detected on imaging is expanding globally. Debate continues over whether variants of uncertain significance (VUS) should be reported prenatally, with some recen...
Twin Anemia Polycythemia Sequence: Pretreatment Characteristics and Outcomes Stratified by Management Approach [0.03%]
双胞胎贫血-红细胞增多序列征的治疗前特点及不同管理策略的效果分析
Camille F Shantz,Karim Ibrahim Dit Nasrallah,Jena L Miller et al.
Camille F Shantz et al.
Objective: To compare Twin Anemia Polycythemia Sequence (TAPS) cases by treatment modality. Methods: Single-center, retrospective revie...
Reference Ranges of Maximum Diameter and Volume of the Fetal Large Intestine During the Second-to Third-Trimester: An MRI Study [0.03%]
基于MRI的胎儿第二至第三孕期结肠径线和容积正常参考值范围研究
Ke Zheng,Minjie Lin,Bingbing Chen et al.
Ke Zheng et al.
Objective: To investigate normal reference ranges for the maximum diameter and volume of the fetal large intestine across the second and third trimesters, and to analyze their correlations with gestational age (GA). ...
Oluwaseun O Babatunde,Madeleine G Bibby,Anthony Atala et al.
Oluwaseun O Babatunde et al.
Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopo...
Placental Dysfunction and Congenital Heart Disease: Investigating the Placenta-Heart Axis [0.03%]
胎盘功能不全与先天性心脏病：探究胎盘-心脏轴
Natalie Lanners,Sarah U Morton,Katherine Le et al.
Natalie Lanners et al.
Objective: Concurrent development of the placenta and heart during early gestation suggests a shared biological basis for the co-occurrence of abnormal placentation and congenital heart disease (CHD). This study investiga...
Prenatal Diagnosis of White-Sutton Syndrome Associated With Autosomal Dominant POGZ Variants Presented With Craniofacial Abnormalities and Borderline Microcephaly Identified in the Second Trimester [0.03%]
产前诊断出与自动显性POGZ变异相关的White-Sutton综合征并伴有颅面畸形和边线微小头症案例
Ping Liu,Hong-Yu Luo,Dong-Zhi Li
Ping Liu
Case Reports
Prenatal diagnosis. 2026 Jun 4. DOI:10.1002/pd.70193 2026