Therapeutic Silencing of Tmprss6 Reduces Iron-Induced Inflammation and Prolongs Survival in MDS Mice [0.03%]
TMPRSS6治疗沉默可减少铁诱导的炎症并延长MDS小鼠生存期
Shahla Vilcassim,Nuttanan Pholngam,Rattanawan Thubthed et al.
Shahla Vilcassim et al.
Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic disorders characterized by ineffective hematopoiesis, cytopenias, and an increased risk of progression to acute myeloid leukemia (AML). Despite advances in su...
Development and Validation of a Novel Conditional Event-Free Survival Tool in Diffuse Large B-Cell Lymphoma [0.03%]
弥漫性大B细胞淋巴瘤的新型条件性无事件生存预测工具的开发和验证
Zhengming Chen,Danny Luan,Rasmus Rask Kragh Jørgensen et al.
Zhengming Chen et al.
One quarter of patients with diffuse large B-cell lymphoma (DLBCL) who achieve a complete response following front-line therapy will eventually experience disease relapse. Existing prognostic models use baseline factors to predict outcomes ...
Patterns of Progression and Clinical Outcomes After First Progression in Patients With Primary Plasma Cell Leukemia [0.03%]
初治原发性浆细胞白血病患者的疾病进展模式及首次进展后的临床预后分析
Daniel G Packard,Shaji K Kumar,Angela Dispenzieri et al.
Daniel G Packard et al.
Primary plasma cell leukemia (pPCL) is a rare and aggressive plasma cell disorder with inferior outcomes compared with multiple myeloma (MM). However, studies describing outcomes after first progression and subsequent lines of therapy remai...
Exploring the Burden on Patients Living With and Receiving Treatment for Immune Thrombocytopenia (ITP): Patient and Physician Perceptions From the ITP World Impact Survey (I-WISh) 2.0 [0.03%]
从ITP患者和医生的视角探索免疫性血小板减少症(ITP)患者的疾病负担:ITP全球影响调查(I-WISh)2.0结果分析
Nichola Cooper,James Bussel,Waleed Ghanima et al.
Nichola Cooper et al.
Limited data exist on how patients and physicians perceive immune thrombocytopenia (ITP) symptoms and treatment-related burden. I-WISh (ITP World Impact Survey) 2.0 surveyed 1018 patients and 431 physicians in 15 countries to characterize t...
Clinically Relevant Bleeding in Individuals With Cancer: Insights From a Nationwide Cohort Study [0.03%]
癌症患者的临床相关出血:全国队列研究的见解
Ming Y Lim,Radhika Gangaraju,Omid Jafari et al.
Ming Y Lim et al.
Cancer care is often complicated by coagulopathy leading to thrombosis and bleeding. While venous thromboembolism (VTE) has been extensively studied, bleeding remains an underestimated threat. To address this knowledge gap, we leveraged the...
JAKPOT Prediction Rule for Erythrocytosis: External Validation and Cost-Effectiveness Analysis [0.03%]
JAKPOT预测规则的红细胞增多症诊断价值及成本效益分析
Barbara D Lam,Satoko Ito,Justine Ryu et al.
Barbara D Lam et al.
Distribution of Gastrointestinal and Dietary Risk Factors Among U.S. Adults Classified as Having Iron Deficiency Anemia Across Diagnostic Thresholds [0.03%]
根据不同诊断界值美国缺铁性贫血成人患者胃肠及饮食风险因素分布状况研究
Omar Al Taani,Bridget M Mayrer,Nicole M Luche et al.
Omar Al Taani et al.
Treatment Patterns and Clinical Outcomes After Immunotherapy Failure in Patients With Natural Killer/T-Cell Lymphoma [0.03%]
NK/T细胞淋巴瘤免疫治疗失败后的治疗模式和临床结局分析
Shenrui Bai,Yongping Song,Liang Wang et al.
Shenrui Bai et al.
Distinct Longitudinal Patterns of Basal and Squamous Cell Carcinoma in Polycythemia Vera and Essential Thrombocythemia [0.03%]
真性红细胞增多症和原发性血小板增多症基底细胞癌和鳞状细胞癌的不同纵向发展规律
Giuseppe G Loscocco,Naseema Gangat,Paola Guglielmelli et al.
Giuseppe G Loscocco et al.