Predicting Early Mortality in Newly Diagnosed AL Amyloidosis: Development and Validation of the PACE Score for Daratumumab-Treated Patients [0.03%]
达鲁莫单抗治疗新型轻链淀粉样变性早期死亡风险的预测模型:PACE评分的研发和验证
George S Mellgard,Abdul-Hamid Bazarbachi,Saurabh Zanwar et al.
George S Mellgard et al.
Systemic AL amyloidosis is a clonal plasma cell dyscrasia, where toxic free light chains (FLCs) lead to vital organ damage, with risk of early mortality despite effective therapies. Notably, there is a paucity of data on the incidence and p...
Evaluating the Impact of Fewer Frontline Intensive Chemotherapy Plus Venetoclax Consolidation Cycles on Outcomes in AML [0.03%]
评估减少强化化疗联合venetoclax维持治疗疗程对AML患者预后的影响
Jennifer Marvin-Peek,Hagop Kantarjian,Wei-Ying Jen et al.
Jennifer Marvin-Peek et al.
Cryopreservation of Hemopoietic Cells for Allotransplant: Altered Immune Cell Subsets and Clinical Implications [0.03%]
同种移植造血细胞冷冻保存:免疫亚群变化及其临床意义
Anna Maria Raiola,Paola Contini,Massimiliano Gambella et al.
Anna Maria Raiola et al.
Cryopreservation of allogeneic peripheral blood stem cells was widely adopted during the SARS-CoV-2 pandemic. We evaluated transplant-related complications and graft product composition in a retrospective (n = 62) and prospective (n = 47) s...
A Phase 4 Trial to Describe the Immunogenicity, Safety, and Tolerability of MenB-fHbp in Participants > 10 Years of Age With Asplenia or Complement Deficiency [0.03%]
一项描述MenB-fHbp免疫原性、安全性和耐受性的10岁以上无脾或补体缺陷患者的期4试验
Lukáš Homola,Piotr Korbal,Isaac Thomsen et al.
Lukáš Homola et al.
Impact of Total Body Irradiation Dose in Reduced-Intensity Conditioning for Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid Leukemia [0.03%]
减强度预处理方案中全身照射剂量在急性髓系白血病异基因造血细胞移植中的影响
Shohei Mizuno,Akiyoshi Takami,Koji Kawamura et al.
Shohei Mizuno et al.
Using data from a nationwide Japanese registry, we evaluated the impact of the total body irradiation (TBI) dose in reduced-intensity conditioning (RIC) for allogeneic hematopoietic cell transplantation (allo-HCT) in patients with acute mye...
Hagop Kantarjian,Helen T Chifotides,Fadi G Haddad et al.
Hagop Kantarjian et al.
It is an exciting era in leukemia owing to the development of novel targeted therapies and advances in genomics, pathophysiology, prognostication, and monitoring (e.g., highly sensitive measurable residual disease assays). Currently, most l...
Sex-Related Differences in Clinical Features, Inflammatory Cytokines, Mutation Topography, Outcomes, and Prognostic Models in Patients With Myeloproliferative Neoplasms [0.03%]
真性红细胞增多症患者临床特征、炎症因子、突变部位、预后及相关危险因素的性别差异研究
Songyang Zhao,Xin Wang,Bing Li et al.
Songyang Zhao et al.
Genetic Contribution to Asthma Informs Acute Chest Syndrome Pathophysiology and Risk Stratification [0.03%]
哮喘的遗传贡献对急性胸腔综合症的病理生理及风险分层提供信息
Sara El Aouhel,Vanessa Bellegarde,Stennio Da Silva Faria et al.
Sara El Aouhel et al.
Acute chest syndrome (ACS) is a severe complication of sickle cell disease (SCD) occurring in ~50% of patients, some presenting frequent episodes. We lack tools to identify patients at high risk of ACS occurrence or frequent episodes. Epide...
Diagnosis and Management of Acute Chest Syndrome in Children With Sickle Cell Disease [0.03%]
sickle细胞病患儿急性胸部综合症的诊断与治疗
Thomas C Fisher-Heath,Colin Rogerson,Benjamin Nti et al.
Thomas C Fisher-Heath et al.
Minutes Matter: An Audit of the Timeliness of Opioid Administration for Sickle Cell Disease Pain in the Emergency Department and Association With Disposition [0.03%]
时机至关重要:对急诊科镰状细胞病疼痛管理中阿片类药物给药及时性的审计及其与患者去向的关系
Ibrahim Gwarzo,Harish Chandra Dega,David C Brousseau
Ibrahim Gwarzo