Dipan Roy,Poonam Mehra,Lisa Clark et al.
Dipan Roy et al.
Reactive oxygen species function as key signals in plant adaptation to environmental stresses like drought. Roots respond to transient water unavailability by temporarily ceasing branching through the acclimative response xerobranching. In ...
Carbonyl-to-sulfur swap enabled by sequential double carbon-carbon bond activation [0.03%]
连续两次碳碳键活化介导的酮基到硫基转换反应
Zining Zhang,Guangbin Dong
Zining Zhang
In drug development, replacement of a skeletal carbon with a sulfur atom can result in analogs of bioactive compounds with improved properties. Currently, the sulfur analogs are almost exclusively prepared by de novo synthesis; the existing...
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction [0.03%]
BBO-10203通过阻断RAS-PI3Kα相互作用抑制肿瘤生长而不引起高血糖症
Dhirendra K Simanshu,Rui Xu,James P Stice et al.
Dhirendra K Simanshu et al.
BBO-10203 is an orally available drug that covalently and specifically binds to the RAS-binding domain of phosphoinositide 3-kinase α (PI3Kα), preventing its activation by HRAS, NRAS, and KRAS. It inhibited PI3Kα activation in tumors wit...
Patrick L Brezonik
Patrick L Brezonik
Bottom sediments are important for nitrogen production in inland and coastal waters.
Carey D Nadell,Christopher J Marx
Carey D Nadell
Bacteria leverage a secretion system to kill and scavenge nutrients from nearby competitors.
Erratum for the Research Article "La- and Mn-doped cobalt spinel oxygen evolution catalyst for proton exchange membrane electrolysis" by L. Chong et al [0.03%]
李崇等发表的研究文章“镧、锰掺杂尖晶石型钴催化剂用于 proton exchange膜电解水制氧”勘误公告
Published Erratum
Science (New York, N.Y.). 2025 Jun 12;388(6752):eadz5020. DOI:10.1126/science.adz5020 2025
Rethinking jaundice [0.03%]
再思黄疸
Joachim Kloehn,Dominique Soldati-Favre
Joachim Kloehn
A buildup of unconjugated bilirubin may be a protective response to malaria.
Yan Yan Shery Huang,Lining Arnold Ju
Yan Yan Shery Huang
A computational algorithm can render a complex artificial vascular structure in minutes.
Bridging the divide: Why the science-policy interface matters for global food systems [0.03%]
弥合分歧：科学政策界面为何对全球粮食系统至关重要
Ismahane Elouafi
Ismahane Elouafi
For decades, empirical evidence has pointed to the unsustainable trajectory of global food systems, linking industrialized production to soil degradation, water stress, and nutrition deficits across vulnerable populations and underscoring t...
Anna-Liisa Laine,Sara Leino
Anna-Liisa Laine
Rising temperatures change the structure and function of plant microbial communities.