Sara Gerke,David A Simon
Sara Gerke
Recent case law can shape how innovation unfolds.
A Rotenberg,M Gunning,R Magistro Nadler et al.
A Rotenberg et al.
A no-fault compensation scheme may help balance innovation and patient protection.
Rapid model-guided design of organ-scale synthetic vasculature for biomanufacturing [0.03%]
基于快速模型引导的器官尺度合成血管生物制造设计
Zachary A Sexton,Dominic Rütsche,Jessica E Herrmann et al.
Zachary A Sexton et al.
Our ability to produce human-scale biomanufactured organs is limited by inadequate vascularization and perfusion. For arbitrarily complex geometries, designing and printing vasculature capable of adequate perfusion poses a major hurdle. We ...
Differential absorption of circularly polarized light by a centrosymmetric crystal [0.03%]
centro-symmetric晶体圆偏振光的吸收差异性
Katherine A Parrish,Andrew Salij,Kendall R Kamp et al.
Katherine A Parrish et al.
Crystalline solids are governed by universal structure-property relationships derived from their crystal symmetry, leading to paradigmatic rules on what properties they can and cannot exhibit. A long-held structure-property relationship is ...
Sam Yeaman
Sam Yeaman
Wild plant species harbor a vast but largely unknown diversity of temperature stress solutions.
Pan-viral ORFs discovery using massively parallel ribosome profiling [0.03%]
利用大规模并行核糖体占有测序进行泛病毒型ORF发现
Shira Weingarten-Gabbay,Matthew R Bauer,Alexandra C Stanton et al.
Shira Weingarten-Gabbay et al.
Defining viral proteomes is crucial to understanding viral life cycles and immune recognition but the landscape of translated regions remains unknown for most viruses. We have developed massively parallel ribosome profiling (MPRP) to determ...
Evolutionary-scale enzymology enables exploration of a rugged catalytic landscape [0.03%]
基于进化的酶学研究能够探索崎岖多变的催化地形
Duncan F Muir,Garrison P R Asper,Pascal Notin et al.
Duncan F Muir et al.
Quantitatively mapping enzyme sequence-catalysis landscapes remains a critical challenge in understanding enzyme function, evolution, and design. In this study, we leveraged emerging microfluidic technology to measure catalytic constants-kc...
Ana Figueiredo,Sonia Trikha Rastogi,Susana Ramos et al.
Ana Figueiredo et al.
Jaundice is a common presentation of Plasmodium falciparum malaria, which arises from the accumulation of circulating bilirubin. It is not understood whether it represents an adaptive or maladaptive response to Plasmodium spp. infection. We...
Adrian Cho
Adrian Cho
"You're killing a newborn baby," says one astrophysicist.
Warren Cornwall
Warren Cornwall
Technology could be a boon for science, but raises ethical concerns.