Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization [0.03%]
人类端粒酶二聚体的低温电镜结构揭示了H/ACA核糖核酸蛋白复合物介导的二聚作用
Sebastian Balch,Zala Sekne,Elsa Franco-Echevarría et al.
Sebastian Balch et al.
Telomerase ribonucleoprotein (RNP) synthesizes telomeric repeats at chromosome ends using a telomerase reverse transcriptase (TERT) and a telomerase RNA (hTR in humans). Previous structural work showed that human telomerase is typically mon...
Katie Langin
Katie Langin
Funding cuts threaten jobs at all levels. "It's a nightmare," one faculty member says.
In Science Journals [0.03%]
科学期刊中的内容
Sacha Vignieri,Sarah H Ross,Phil Szuromi et al.
Sacha Vignieri et al.
Highlights from the Science family of journals.
Atomic explosion [0.03%]
原子爆炸
Adrian Cho
Adrian Cho
Quantum computers fashioned out of individual atoms are poised to lead the field.
In Other Journals [0.03%]
他刊述要
Yevgeniya Nusinovich,L Bryan Ray,Brad Wible et al.
Yevgeniya Nusinovich et al.
Editors' selections from the current scientific literature.
Robert F Service
Robert F Service
NIH has not committed to continuing support for contest that inspired AI tools for predicting how proteins would fold.
Single- and multithread rivers originate from (im)balance between lateral erosion and accretion [0.03%]
侧向侵蚀和堆积的平衡状态决定了河流单分汊或多分汊的状态
Austin J Chadwick,Evan Greenberg,Vamsi Ganti
Austin J Chadwick
Why river channels confine flow to a single pathway or divide flow into multiple interwoven pathways (threads) forms a long-standing fundamental question in river science, which to date remains poorly understood. In this study, we probed ch...
Overturning circulation structures the microbial functional seascape of the South Pacific [0.03%]
大洋环流塑造南太平洋微生物功能景观
Bethany C Kolody,Rohan Sachdeva,Hong Zheng et al.
Bethany C Kolody et al.
Global overturning circulation partitions the deep ocean into regions, each with different physicochemical characteristics, but the extent to which these water masses represent distinct ecosystems remains unknown. In this work, we integrate...
Samantha A Keil,Deidre Jansson,Molly Braun et al.
Samantha A Keil et al.
Thirteen years after the initial publication defining the glymphatic system, we critically reappraise the role of its dysfunction in Alzheimer's disease (AD). Our understanding of glymphatic function and its involvement in the pathogenesis ...
Kimberly A Powers,Justin Lessler,Stephen R Cole et al.
Kimberly A Powers et al.