Ultracompact on-chip spectral shaping using pixelated nano-opto-electro-mechanical gratings [0.03%]
用于片上光谱整形的像素化纳米光电机械光栅
Weixin Liu,Siyu Xu,Chengkuo Lee
Weixin Liu
The ability to shape light spectra dynamically and arbitrarily would revolutionize many photonic systems by offering unparalleled spectral efficiency and network flexibility. However, most existing optical components have rigid spectral fun...
Dysfunction in primate dorsolateral prefrontal area 46 affects motivation and anxiety [0.03%]
恒河猴背外侧前额叶区域46的异常影响动机和焦虑反应
Christian M Wood,Rana Banai Tizkar,Martina Fort et al.
Christian M Wood et al.
The dorsolateral prefrontal cortex (dlPFC) is a higher-order brain structure targeted for noninvasive stimulation for treatment-resistant depression. Nonetheless, its causal role in emotion regulation is unknown. We discovered that inactiva...
Load and lock: An emerging class of therapeutics that influence macromolecular dissociation [0.03%]
负载与锁定：一类影响大分子解离的新兴药物类群
Raymond J Deshaies,Patrick Ryan Potts
Raymond J Deshaies
Biology is governed by macromolecular interactions, perturbation of which often lies at the heart of disease. Most therapeutic drugs, whether they are small molecules or biologics, exert their effects through impeding such interactions, whe...
Faced with 'impossible' workload, USDA struggles to oversee lab animal welfare [0.03%]
面临“不可能”的工作量 美国农业部难以监管实验动物福祉问题
David Grimm
David Grimm
Shrinking staff and other handicaps threaten enforcement of the Animal Welfare Act.
Haoxiang Yang,Jinrui Xun,Yajuan Li et al.
Haoxiang Yang et al.
Lysosomal vacuolation is commonly found in many pathophysiological conditions, but its molecular mechanisms and functions remain largely unknown. Here, we show that the endoplasmic reticulum (ER)-anchored lipid transfer protein PDZ domain-c...
Overcoming energy disorder for cavity-enabled energy transfer in vibrational polaritons [0.03%]
克服能量无序性实现腔室辅助振动极化激元能量转移
Guoxin Yin,Tianlin Liu,Lizhu Zhang et al.
Guoxin Yin et al.
Energy disorder is ubiquitous in chemistry and physics. It can suppress polariton delocalization by disrupting molecular coherence-limiting polariton-modified properties. We investigated how energy disorders affect vibrational polariton dyn...
Jackie Leach Scully
Jackie Leach Scully
Nothing succeeds like success, we are told, and certainly that seems true for artificial intelligence (AI). It is hard to overstate either the ubiquity or the success of AI-based technologies in science and technology, health research and c...
Discovering Denisova The Secret World of Denisovans Silvana Condemi and François Savatier The Experiment, 2025. 272 pp [0.03%]
Denisova：发现 Denis 灵长世界：Condemi 和 Savatier 的秘密世界 Denisovan
Brenna R Hassett
Brenna R Hassett
A pair of authors invite readers to get to know the elusive archaic human.
Brent S Pease,Neil A Gilbert
Brent S Pease
Light pollution disrupts light-dark cues that organisms use as timetables for life. Although studies-typically focusing on individual species-have documented earlier morning onset of bird vocalization in light-polluted landscapes, a synthes...
Probing the pain [0.03%]
探究疼痛之谜
Meredith Wadman
Meredith Wadman
Katie Burns is helping uncover the role of the immune system in endometriosis-while managing her own disease.