H Holden Thorp
H Holden Thorp
The renowned American management consultant and author Peter Drucker is often credited as saying that "the best way to predict the future is to create it"-a view that applies to science as much as to the business world. It implies that gain...
Michael S Harris
Michael S Harris
Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation [0.03%]
原位基因组测序揭示核异常与染色质调控异常的关联
Ajay S Labade,Zachary D Chiang,Caroline Comenho et al.
Ajay S Labade et al.
Microscopy and genomics are used to characterize cell function, but approaches to connect the two types of information are lacking, particularly at subnuclear resolution. Here, we describe expansion in situ genome sequencing (ExIGS), a tech...
Kishore Jaganathan,Nicole Ersaro,Gherman Novakovsky et al.
Kishore Jaganathan et al.
Only a minority of patients with rare genetic diseases are currently diagnosed by exome sequencing, suggesting that additional unrecognized pathogenic variants may reside in non-coding sequence. Here, we describe PromoterAI, a deep neural n...
Pre-European contact leprosy in the Americas and its current persistence [0.03%]
美洲接触欧洲前麻风病及其目前的持续存在
Maria Lopopolo,Charlotte Avanzi,Sebastian Duchene et al.
Maria Lopopolo et al.
Leprosy, primarily caused by Mycobacterium leprae, is considered a disease introduced into the Americas during European colonization. However, the recent discovery of a second pathogen causing leprosy, M. lepromatosis, mainly found in the A...
Cymene Howe,Dominic Boyer
Cymene Howe
More than three-quarters of global glacier mass is projected to disappear under present-day policies.
Andriy H Nevidomskyy
Andriy H Nevidomskyy
Experimental observations provide clues to understanding an enigmatic superconductor, uranium ditelluride.
A wave of emotion [0.03%]
一波情感的涌动
Stoyo Karamihalev,Nadine Gogolla
Stoyo Karamihalev
Sustained brainwide patterns of activity enable emotions to outlast their triggers.