An orthogonal T7 replisome for continuous hypermutation and accelerated evolution in E. coli [0.03%]
一个正交的T7 replisome体系在大肠杆菌中实现持续的高突变率及其进化速率的提升
Christian S Diercks,Philipp Sondermann,Cynthia Rong et al.
Christian S Diercks et al.
Systems that perform continuous hypermutation of designated genes without compromising the integrity of the host genome can substantially accelerate the evolution of new or enhanced protein functions. We describe an orthogonal DNA replicati...
Andre Giles,Bernardo M Flores
Andre Giles
Revisiting the human sociobiology debate Sociobiology: The New Synthesis Edward O. Wilson Harvard University Press, 1975. 697 pp [0.03%]
重议人类社会生物学之论战《社会生物学》——新的综合爱德华·O.威尔逊哈佛大学出版社，1975年，697页
Gillian R Brown,H Clark Barrett,Kevin N Lala
Gillian R Brown
What have we learned 50 years on?
Evolution of antiviral host defenses against a backdrop of endogenous retroelements [0.03%]
以内源性逆转录病毒为背景的抗病毒宿主防御进化
George Kassiotis,Jonathan P Stoye
George Kassiotis
Mammalian hosts deploy a multitude of germ line-encoded mechanisms to detect and restrict virus infection. These mechanisms must avoid pathological responses to endogenous retroviruses and other endogenous retrotransposable elements (RTEs)-...
Erik Stokstad
Erik Stokstad
Hybridization 9 million years ago gave potatoes the genetic knack to develop tubers, a new study finds.
Jocelyn Kaiser
Jocelyn Kaiser
Bipartisan support for agency challenges proposed reorganization and overhead costs cap.
Sangwon Lee,Michael Pilipchuk,Can Yildirim et al.
Sangwon Lee et al.
At two-thirds the weight of aluminum, magnesium alloys have the potential to reduce the fuel consumption of transportation vehicles. These advancements depend on our ability to optimize the desirable versus undesirable effects of deformatio...
Annika Inampudi
Annika Inampudi
iPsych, which investigates the genetics of psychiatric disorders, has sent 140,000 opt-out notices amid backlash.
Strain-coupled, crystalline polymer-inorganic interfaces for efficient magnetoelectric sensing [0.03%]
高效的磁电传感用应变耦合结晶聚合物-无机界面
Binbin He,Yuanyuan He,Wenhui Wang et al.
Binbin He et al.
Magnetoelectric sensing holds promise for flexible sensors, offering precise detection of both electric and magnetic fields with minimal power consumption. However, its practical use has been constrained by weak magnetoelectric effects and ...
New Products [0.03%]
新产品动态
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.