Nitric oxide as a biomarker for patients with endometriosis: a systematic review and meta-analysis [0.03%]
一氧化氮可作为子宫内膜异位症患者的生物标志物吗?系统评价和-meta-分析
Kelly Campara,Patrícia Rodrigues,Fernanda Tibolla Viero et al.
Kelly Campara et al.
Background: Endometriosis causes pelvic pain, inflammation, and increased oxidative stress levels. To assist in the diagnosis of endometriosis and molecular mechanisms, we propose synthesize the studies that NO levels in ...
Catestatin alleviates PASMC phenotypic switching-mediated pulmonary arterial remodeling in a rat model of MCT-induced pulmonary arterial hypertension by promoting endothelium-derived NO synthesis [0.03%]
катестатин通过促进内皮源性一氧化氮的合成缓解MCT诱导肺动脉高压大鼠模型中的PASMC表型转化介导的肺动脉重构
Zheyu Liu,Bo Cui,Hao Ju et al.
Zheyu Liu et al.
Background: Enhancing the nitric oxide (NO) signaling pathway is an effective strategy for treating pulmonary arterial hypertension (PAH). Previous research has found that Catestatin (CST) exerts a negative inotropic effe...
SIRT3 Sulfhydrylation by Hydrogen Sulphide: A Novel Approach to Prevent Ferroptosis and Atrial Fibrosis [0.03%]
H2S介导的SIRT3硫化修饰:预防铁死亡和房颤的新机制
Zi-Zhu Zhang,Xiu-Heng Wang,Zhi-Hong Ning et al.
Zi-Zhu Zhang et al.
Background: Hydrogen sulfide (H2S) has been shown to counteract ferroptosis and atrial fibrosis, yet the underlying mechanisms remain incompletely understood. This study aims to investigate how H2S regulates ferroptosis t...
3-mercaptopyruvate sulfurtransferase resides on the inner mitochondrial membrane [0.03%]
三甲基硫转移酶位于线粒体内的膜上
Antonia Katsouda,Eleni Vasilaki,Markos Fountoulakis et al.
Antonia Katsouda et al.
3-mercaptopyruvate sulfurtransferase (MPST) is an enzyme implicated in the generation of the gasotransmitter hydrogen sulfide (H2S). Unlike, the other two H2S-synthesizing enzymes cystathionine gamma lyase (CSE) and cystathionine beta synth...
Inorganic Nitrate Stores, Astrocyte Metabolism and Brain Health: An Emerging Paradigm [0.03%]
无机硝酸盐储存、星形胶质细胞代谢与脑健康:新兴理论框架
Mario Siervo,Giuseppe Verdile,Barbora Piknova
Mario Siervo
Inorganic nitrate plays a crucial role in the regulation of cerebral blood flow and neurotransmission through its conversion to nitric oxide (NO). Astrocytes are star-shaped glial cells and contribute to maintain the blood-brain barrier int...
Appearances can be deceiving: differences in FeNO values among COPD and severe asthmatic patients stratified according to peripheral eosinophilic count [0.03%]
表象往往具有欺骗性:根据外周血嗜酸性粒细胞计数对慢性阻塞性肺疾病和重症哮喘患者FeNO值进行分层分析后的差异
Claudio Candia,Silvestro Ennio DAnna,Maria DAmato et al.
Claudio Candia et al.
Eosinophilic COPD (eCOPD) and eosinophilic severe asthma (eSA) appear to share relevant clinical features, including responsiveness to steroids and higher exacerbation rates. However, data on the expression of T2-high inflammation biomarker...
Impact of Low Nitrate/Nitrite Diet and Nitrate Supplementation on Litter Size and Fetal and Placental Growth in Pregnant Mice [0.03%]
低硝酸盐/亚硝酸盐饮食和硝酸盐补充对小鼠胎仔数及胎儿和胎盘生长的影响
Hager M Kowash,Teresa Tropea,Mark R Dilworth et al.
Hager M Kowash et al.
Background: In pregnancy, nitric oxide (NO) plays important roles in embryo development, maternal cardiovascular function, fetoplacental blood flow and fetal growth. Whilst the importance of NO synthase (NOS)-derived NO h...
Biomechanical study on the effect of changes in ostiomeatal complex structure on NO concentration in the nasal cavity [0.03%]
鼻腔结构变化对鼻腔一氧化氮浓度影响的生物力学研究
Shen Yu,Xiaojun Xie,Danqing Wang et al.
Shen Yu et al.
Background: Nitric oxide (NO) concentration in the nasal cavity plays an important role in maintaining nasal function and health. We investigated the influence of the geometric structure of the ostiomeatal complex (OMC) o...
Antagonistic effect of a nitric oxide donor agents based on ruthenium complex combined with cisplatin on lung tumor cell lines [0.03%]
基于钌复合物的供氮氧化物制剂与顺铂作用于肺癌细胞系的拮抗效应研究
Angelica E Graminha,Amanda B Becceneri,Raffaela Rios et al.
Angelica E Graminha et al.
Nitric oxide (NO) is a versatile biological messenger involved in numerous physiological processes and anticancer mechanisms. Its functions are highly dependent on its concentration and the specific site of action. In this study, we investi...
Targeting inducible nitric oxide synthase with 1400W mitigates septic acute lung injury through inhibiting SLC7A11/GPX4 mediated ferroptosis [0.03%]
靶向诱导型一氧化氮合酶抑制SLC7A11/GPX4介导的铁死亡从而缓解脓毒症急性肺损伤
Zi-Yao Wang,Tao Zeng,Xin Wang et al.
Zi-Yao Wang et al.
Accumulating evidence has indicated that lung ferroptosis is an important contributor to septic acute lung injury (SALI). Inducible nitric oxide synthase (iNOS) may be implicated in the regulation of bronchial epithelial ferroptosis. Nevert...