Involvement of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) levels in precancerous and cancerous cervical lesions [0.03%]
内皮型一氧化氮合酶(eNOS)及一氧化氮(NO)在宫颈癌前及癌组织中的表达水平及其相关性研究
Jaweher Bday,Moufida Souid,Karim H Farhat et al.
Jaweher Bday et al.
To assess the role of endothelial nitric oxide synthase (eNOS) in cervical cancer, we investigated the association between eNOS -786T/C and intron 4 VNTR 4b/a eNOS gene variations, plasma nitric oxide (NO) levels, cervical lesion occurrence...
Corrigendum to "Cannabidiol induces systemic analgesia through activation of the PI3Kγ/ nNOS/NO/KATP signaling pathway in neuropathic mice. A KATP channel S-nitrosylation-dependent mechanism" [Nitric Oxide 146 (2024) 1-9] [0.03%]
关于“ cannabidiol通过激活PI3Kγ/nNOS/NO/KATP信号通路在神经病理性小鼠中诱导全身镇痛。一种依赖于KATP通道S-亚硝基化的作用机制”[《一氧化氮》146 (2024) 1-9]的勘误表
Douglas Lamounier de Almeida,Renata Cristina Mendes Ferreira,Flávia Cristina Fonseca et al.
Douglas Lamounier de Almeida et al.
CYR119, a central nervous system-penetrant stimulator of soluble guanylyl cyclase, improves survival in a mouse model of resuscitation after cardiac arrest [0.03%]
一种可以穿透中枢神经系统的可溶性鸟苷酸环化酶刺激剂CYR119可在心脏骤停复苏小鼠模型中改善生存率
Alexandra Marenco,Yusuke Miyazaki,Melanie Cruz Santos et al.
Alexandra Marenco et al.
Background: Treatment with inhaled nitric oxide (NO) improves rates of survival and neurologic outcomes in a mouse model of resuscitation after cardiac arrest. The effect of NO is dependent on the soluble guanylyl cyclase...
Unsaturated fatty acids identified as reversible soluble guanylyl cyclase inhibitors [0.03%]
不饱和脂肪酸被确定为可逆的可溶性鸟苷酸环化酶抑制剂
Simon Gissing,Eva-Maria Pferschy-Wenzig,Ramona Jeitler et al.
Simon Gissing et al.
As key enzyme in the NO/cGMP pathway, soluble guanylyl cyclase (sGC) has become an important therapeutic target in the treatment of cardiovascular diseases. In addition to activating compounds, inhibitors of sGC are necessary tools in resea...
Roles of nitric oxide in improving post-harvest horticultural product quality: Crosstalk with hydrogen sulfide [0.03%]
一氧化氮在改善采后园艺产品品质中的作用:与硫化氢的相互作用
Yali Qiao,Yayu Liu,Jihua Yu et al.
Yali Qiao et al.
Postharvest quality maintenance is a key research focus in horticultural science. Nitric oxide (NO), a vital gaseous signaling molecule, significantly improves postharvest quality by inhibiting ethylene (ETH) synthesis, reducing respiration...
A Versatile Vanadium(III)-Based Chemiluminescence Protocol for Nitric Oxide Metabolite Quantification and NO Release Kinetics [0.03%]
一种通用的钒(III)化学发光协议,用于一氧化氮代谢物定量及一氧化氮释放动力学研究
Joseph A Bauer,Annette M Sysel,Michael J Dunphy
Joseph A Bauer
Nitric oxide (NO) is a central mediator of vascular, neurological, and immune functions, and its dysregulation is implicated in a broad spectrum of diseases. Despite its significance, direct measurement of NO in human samples is limited by ...
NITRIC OXIDE FUNCTIONAL RELATIONSHIPS WITH NITROGEN-CONTAINING STRESS METABOLITES: ROLE IN PLANT ADAPTATION TO ADVERSE ABIOTIC FACTORS [0.03%]
一氧化氮与含氮应激代谢产物的功能关系:适应不利非生物因素的作用
Yuriy E Kolupaev,Tetiana O Yastreb,Alla Yemets et al.
Yuriy E Kolupaev et al.
Polyamines, γ-aminobutyric acid (GABA), proline, and glycine betaine (GB) are important plant stress metabolites that are interconnected in common metabolic cycles. These compounds have a multifunctional protective effect on plant cells un...
Zahra Bahadoran,Asghar Ghasemi
Zahra Bahadoran
Diabetic peripheral neuropathy (DPN) is one of the most prevalent long-term complications in type 1 (T1DM) and type 2 (T2DM) diabetes mellitus and is characterized by structural (microangiopathy, axonal atrophy, impaired myelination, and di...
Sajad Jeddi,Khosrow Kashfi,Asghar Ghasemi
Sajad Jeddi
Diabetic nephropathy (DN) is characterized by structural kidney alterations-including glomerular basement membrane thickening, mesangial expansion, tubulointerstitial fibrosis, and glomerular hypertrophy-alongside functional impairments suc...
5-HT7 receptor antagonist SB269970 attenuates seizures by modulating NO/cGMP signaling pathway and neuroinflammation in a pentylenetetrazol-induced epilepsy model in rats [0.03%]
五氟利多诱导的癫痫模型中,5-ht7受体拮抗剂sb269970通过调节no/cgmp信号通路和神经炎症抑制癫痫发作
Handan Gunes,Ercan Ozdemir,Ahmet Sevki Taskiran
Handan Gunes
Epilepsy is a disease affecting the quality of life, characterized by neuronal excessive discharges resulting from the disruption of the balance between excitatory and inhibitory systems in the brain, and its pathophysiology has not been fu...