Enantioselective Synthesis of Hydrobenzofuranones Using an Asymmetric Desymmetrizing Intramolecular Stetter Reaction of Cyclohexadienones [0.03%]
环己二酮的不对称脱对称化 intramolecular stetter 反应合成手性氢化苯并呋喃酮化合物
Qin Liu,Tomislav Rovis
Qin Liu
A series of cyclohexadienones were synthesized by dearomatization of phenols followed by Dess-Martin oxidation. Asymmetric intramolecular Stetter reactions of these substrates provide hydrobenzofuranones in good to excellent yields and exce...
Refined Synthesis of 2,3,4,5-Tetrahydro-1,3,3-trimethyldipyrrin, a Deceptively Simple Precursor to Hydroporphyrins [0.03%]
2,3,4,5-四氢-1,3,3-三甲基二吡咯的精简合成：一种合成杂环卟啉的前体化合物
Marcin Ptaszek,Jayeeta Bhaumik,Han-Je Kim et al.
Marcin Ptaszek et al.
2,3,4,5-Tetrahydro-1,3,3-trimethyldipyrrin (1) is a crucial building block in the rational synthesis of chlorins and oxochlorins. The prior 5-step synthesis of 1 from pyrrole-2-carboxaldehyde (2) employed relatively simple and well-known re...