D C Des Jarlais
D C Des Jarlais
Early in the history of the AIDS epidemic there was clear evidence of differences in the outcomes of HIV infection between injecting drug users and men who have sex with men. There were also some indications that high levels of nonsterile d...
Impact of tuberculosis on the body composition of HIV-infected men in Brazil [0.03%]
巴西HIV感染者身体 Composition 的结核病影响
N I Paton,L R Castello-Branco,G Jennings et al.
N I Paton et al.
Objective: Tuberculosis (TB) is the commonest HIV-related opportunistic infection in many developing countries and is thought to be a frequent underlying cause of HIV-associated wasting. We have used reference water dilut...
HIV infection of the central nervous system is characterized by rapid turnover of viral RNA in cerebrospinal fluid [0.03%]
中枢神经系统的HIV感染的特征是脑脊液中病毒RNA快速周转
C C Eggers,J van Lunzen,T Buhk et al.
C C Eggers et al.
To assess the kinetics of viral replication and decay in cerebrospinal fluid (CSF), we studied the short-term effects of highly active antiretroviral therapy (HAART) on CSF HIV-1 RNA concentrations. In 15 HIV-positive patients, HIV RNA conc...
Lack of association between hepatitis C infection and development of AIDS-related lymphoma [0.03%]
丙型肝炎感染与艾滋病相关淋巴瘤发病无关联
A M Levine,R Nelson,E Zuckerman et al.
A M Levine et al.
Hepatitis C virus (HCV) has been associated with various lymphoproliferative disorders, and a high prevalence (9%-32%) of chronic HCV infection has been demonstrated among patients with lymphoma. Dual coinfection by HIV and HCV has been dem...
Phase II, randomized, open-label, community-based trial to compare the safety and activity of combination therapy with recombinant interferon-alpha2b and zidovudine versus zidovudine alone in patients with asymptomatic to mildly symptomatic HIV infection. HIV Protocol C91-253 Study Team [0.03%]
重组干扰素-a2b与叠氮胸苷联合治疗轻症艾滋病患者的Ⅱ期临床试验：HIV协议C91-253研究小组
S E Krown,D Aeppli,H H Balfour Jr
S E Krown
Objectives: To compare, in a community-based therapeutic setting, the safety, tolerance, and efficacy of combination therapy with recombinant interferon-alpha2b (rIFN-alpha2b) and zidovudine (ZDV) to ZDV monotherapy. ...
Stability of cutaneous anergy in women with or at risk for HIV infection. HIV Epidemiology Research Study Group [0.03%]
HIV感染妇女皮肤免疫耐受的稳定性:HIV流行病学研究小组的一项报告
R S Klein,J Sobel,T Flanigan et al.
R S Klein et al.
Objective: To study the stability of cutaneous anergy in women with or at risk for HIV infection. Design: Prospective multicenter cohor...
Studies of body composition and fat distribution in HIV-infected and control subjects [0.03%]
HIV感染者和对照者身体组成和脂肪分布的研究
D P Kotler,K Rosenbaum,J Wang et al.
D P Kotler et al.
Objective: Recent studies have documented alterations in body fat distribution that have been associated with protease inhibitor therapy. We compared body composition, including measurements of fat distribution, in 96 HIV...
Clinical trials using HIV-1 RNA-based primary endpoints: statistical analysis and potential biases [0.03%]
基于HIV-1 RNA的主要终点的临床试验：统计分析和潜在偏差
I C Marschner,R A Betensky,V DeGruttola et al.
I C Marschner et al.
Clinical trial endpoints based on magnitude of reduction in HIV-1 RNA levels provide an important complement to endpoints based on percentage of patients achieving complete virologic suppression. However, interpretation of magnitude of redu...
Oxandrolone, used for treatment of wasting disease in HIV-1-infected patients, does not diminish the antiviral activity of deoxynucleoside analogues in lymphocyte and macrophage cell cultures [0.03%]
治疗HIV-1感染患者的厌食病的药物氧安德伦不会降低脱氧核苷类似物在淋巴细胞和巨噬细胞培养中的抗病毒活性
D M Segal,M Perez,P Shapshak
D M Segal
Antiviral agents are the primary therapy for patients infected with HIV-1. However, supportive therapies are often necessary in addition to antiviral drugs because of the devastating wasting process associated with HIV-1 infection and AIDS....
S Michaels,P Kissinger
S Michaels