Macrophage immunophenotype but not anti-inflammatory profile is modulated by peroxisome proliferator-activated receptor gamma (PPARγ) in exercised obese mice [0.03%]
运动对肥胖小鼠巨噬细胞免疫表型的重塑独立于PPARγ介导的抗炎效应
Loreana Sanches Silveira,Luana Amorim Biondo,Alexandre Abílio de Souza Teixeira et al.
Loreana Sanches Silveira et al.
Moderate aerobic training may be therapeutic for chronic low-grade inflammatory diseases due to the associated anti-inflammatory response that is mediated by immune cells. The peroxisome proliferator-activated receptor gamma (PPARγ) regula...
The mobilisation of early mature CD56dim-CD16bright NK cells is blunted following a single bout of vigorous intensity exercise in Type 1 Diabetes [0.03%]
1型糖尿病患者在剧烈运动后早期活化CD56dim-CD16bright自然杀伤细胞动员受阻
M Curran,J P Campbell,E Powell et al.
M Curran et al.
Type 1 diabetes (T1D) is a T cell mediated autoimmune disease that targets and destroys insulin-secreting pancreatic beta cells. Although T cell mediated, a number of other immune cells are also critically involved in coordinating the event...
Exercise and the Kynurenine pathway: Current state of knowledge and results from a randomized cross-over study comparing acute effects of endurance and resistance training [0.03%]
运动与犬尿氨酸途径：现状及耐力训练和力量训练的急性效应比较的随机交叉对照试验结果
Niklas Joisten,Felix Kummerhoff,Christina Koliamitra et al.
Niklas Joisten et al.
Introduction: The essential amino acid tryptophan (TRP) is primarily degraded through the kynurenine (KYN) pathway, which is dysregulated in several chronic diseases. KYN pathway metabolites have immune- and neuro-modulat...
Randomized Controlled Trial
Exercise immunology review. 2020:26:24-42. DOI: 2020
Can exercise affect immune function to increase susceptibility to infection? [0.03%]
运动对免疫功能的影响会增加感染的易感性吗？
Richard J Simpson,John P Campbell,Maree Gleeson et al.
Richard J Simpson et al.
Multiple studies in humans and animals have demonstrated the profound impact that exercise can have on the immune system. There is a general consensus that regular bouts of short-lasting (i.e. up to 45 minutes) moderate intensity exercise i...
Review
Exercise immunology review. 2020:26:8-22. DOI: 2020
Benefits of exercise and immunotherapy in a murine model of human non-small-cell lung carcinoma [0.03%]
运动和免疫疗法在人非小细胞肺癌小鼠模型中的益处
Asunción Martín-Ruiz,Carmen Fiuza-Luces,Cecilia Rincón-Castanedo et al.
Asunción Martín-Ruiz et al.
Background: Lung cancer has the highest incidence and mortality rate in the world. One of the most promising new cancer therapies in recent years is immunotherapy, which is based on the blockade of immune checkpoints such...
Mobilizing serum factors and immune cells through exercise to counteract age-related changes in cancer risk [0.03%]
通过锻炼调动血清因素和免疫细胞以对抗年龄相关的癌症风险变化
Ji Hui Hwang,Jacqui McGovern,Geoffrey M Minett et al.
Ji Hui Hwang et al.
An increasing body of evidence suggests that age-related immune changes and chronic inflammation contribute to cancer development. Recognizing that exercise has protective effects against cancer, promotes immune function, and beneficially m...
Review
Exercise immunology review. 2020:26:80-99. DOI: 2020
Key viral immune genes and pathways identify elite athletes with URS [0.03%]
关键病毒免疫基因和途径可识别具有易损性疾病的优秀运动员
Candice Colbey,Michael K Drew,Amanda J Cox et al.
Candice Colbey et al.
Purpose: Habitual intense exercise may increase the incidence of upper respiratory symptoms (URS) in elite athletes. This study investigated whether immune gene expression could identify gene markers that discriminate ath...
Elevating body termperature to reduce low-grade inflammation: a welcome strategy for those unable to exercise? [0.03%]
提高体温以减少低度炎症：对于无法运动的人们而言这是一种可取的策略吗？
Sven P Hoekstra,Nicolette C Bishop,Christof A Leicht
Sven P Hoekstra
Chronic low-grade inflammation is increasingly recognized in the aetiology of a range of chronic diseases, including type 2 diabetes mellitus and cardiovascular disease, and may therefore serve as a promising target in their prevention or t...
Review
Exercise immunology review. 2020:26:42-55. DOI: 2020
Effects of aerobic exercise on molecular aspects of asthma: involvement of SOCS-JAK-STAT [0.03%]
有氧运动对哮喘分子方面的影响：SOCS-JAK-STAT的参与
A R Almeida-Oliveira,Jcj Aquino-Junior,A Abbasi et al.
A R Almeida-Oliveira et al.
Background: Aerobic training (AT) decreases airway inflammation in asthma, but the underlying cellular and molecular mechanisms are not completely understood. Thus, this study evaluated the participation of SOCS-JAK-STAT ...
T and B cell subsets differentially correlate with amyloid deposition and neurocognitive function in patients with amnestic mild cognitive impairment after one year of physical activity [0.03%]
运动一年后遗忘型轻度认知障碍患者中T细胞和B细胞亚群与淀粉样蛋白沉积及神经心理功能的一年纵向相关性研究
Katherine Poinsatte,Emily E Smith,Vanessa O Torres et al.
Katherine Poinsatte et al.
Individuals with amnestic mild cognitive impairment (aMCI) experience cognitive declines in learning and memory greater than expected for normal aging, and are at a high risk of dementia. We previously reported that sedentary aMCI patients ...
Review
Exercise immunology review. 2019:25:34-49. DOI: 2019