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期刊名:Artificial cells blood substitutes and immobilization biotechnology

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ISSN:1073-1199

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Baoguo Jiang,Peixun Zhang,Jiazhi Yan et al. Baoguo Jiang et al.
To observe the biomechanic properties of the sciatic nerve at the suture site following repairing in rats. The right sciatic nerves of 40 white Sprague-Dawley 300~350 gm rats were exposed, cut and then repaired with 10-0 nylon sutures with ...
Christian Rempf,Arno Ritter,Sonja Schrepfer et al. Christian Rempf et al.
We investigated the effect of the bovine hemoglobin based oxygen carrier HBOC-200 (Oxyglobin) in rat aortic endothelial cells (RAEC) on the activation of heme oxygenase 1 (HO-1). RAEC were incubated in the presence of 75 microM (G1) or 225 ...
Kun-Ping Yan,Jing Hao,Ning Dan et al. Kun-Ping Yan et al.
This study introduced a liquid-liquid extraction method designed for complete recovery of phospholipids from protein-rich samples, such as hemoglobin (Hb) solutions. In order to minimize protein denaturation and maximize lipid extraction fr...
C Robert Valeri,Gina Ragno C Robert Valeri
The severe adverse events observed in patients who received hemoglobin based oxygen carriers (HBOCs) were associated with the Ringer's D.L lactate resuscitative solution administered and to the excipient used in the HBOCs containing Ringer'...
Servet Cete,Ahmet Yaşar,Fatma Arslan Servet Cete
In this study, uricase was immobilized by a glutaraldehyde/gelatine crosslinking procedure onto polypyrrole film. The K(m) value for immobilized enzyme 0.44 mM was much higher than that of the free enzyme 0.39 mM. V(max) values were 8.4 x 1...
Jesse P Sullivan,Jason E Gordon,Therese Bou-Akl et al. Jesse P Sullivan et al.
The production of a fully functional bioartificial liver assist device (BLAD) would greatly enhance available treatment options for patients suffering from acute liver failure. Currently, inadequate oxygen provision to hepatocytes seeded wi...
Chunyang Zheng,Jingxiu Bi,Guanghui Ma et al. Chunyang Zheng et al.
Direct conjugation of bovine hemoglobin (Hb) and human serum albumin (HSA) with glutaraldehyde would result in a complex mixture of dimers Hb-Hb, Hb-HSA, HSA-HSA and other oligomers. To obtain a high yield of target Hb-HSA, modulation of th...
Tomoyasu Atoji,Hirotaka Yatami,Motonari Aihara et al. Tomoyasu Atoji et al.
We studied the peroxidase activity of ferrylhemoglobin radical (Hb(Fe(4+) = O*)) generated by the reaction of metHb (Hb(Fe(3+))) with hydrogen peroxide (H(2)O(2)). To clarify the behaviors of ferrylHb radical, it was isolated from the react...