"Use as Directed" Can Cause Confusion for Both Patients and Practitioners [0.03%]
“照说明使用”可能会误导患者和医务人员
Matthew Grissinger
Matthew Grissinger
The familiar but ambiguous sigs on prescriptions are often of limited help to patients and pharmacists. Sometimes, the instruction to "use as directed" has resulted in serious errors.
Trump Administration Announces Long-Awaited Rebate Changes: One Safe Harbor Eliminated, Two Others Created [0.03%]
特朗普政府宣布备受期待的回扣变革：一个“安全港”被取消，另外两个由此产生
Stephen Barlas
Stephen Barlas
The current rebate "safe harbor" encourages drug manufacturers to inflate list prices. The HHS's newly proposed rule threatens to eliminate this safe harbor but offers two new ones instead.
Walter Alexander
Walter Alexander
We report on two presentations on β-thalassemia and myelodysplastic syndromes, three presentations on chronic lymphocytic leukemia, and others on perioperative oral anticoagulation, sickle-cell anemia, diffuse large B-cell lymphoma, and mu...
Routine Use of Vitamin K in the Treatment of Cirrhosis-Related Coagulopathy: Is it A-O-K? Maybe Not, We Say [0.03%]
维生素K用于治疗肝硬化相关凝血障碍的常规使用安全有效吗？未必如此
Sarah M Aldrich,Randolph E Regal
Sarah M Aldrich
Historically, coagulopathy related to cirrhosis has been managed primarily as a bleeding disorder. However, several recent studies have shown that patients with cirrhosis have an increased risk of both bleeding and clotting. These coagulopa...
Jomi Oommen,Judy Chen,Shan Wang et al.
Jomi Oommen et al.
Orthostatic hypotension is defined as a decrease in systolic blood pressure of at least 20 mmHg or a decrease in diastolic blood pressure of at least 10 mmHg (or both), within three minutes of moving from a supine to an upright or standing ...
Lowering the Boom on High Drug Prices: HHS Plans Not a Boon to Some Players [0.03%]
降低高昂的药价？卫生与公众服务部的新规喜忧参半
Stephen Barlas
Stephen Barlas
The Trump administration's multipronged effort to use regulatory tools to lower drug prices includes old and new initiatives. But opposition from some players is evident in each instance. Some of that opposition may be based on sound reason...
Forensic Analysis in Drug Litigation Finds Most Errors Occur with Commonly Used Therapies and Practices [0.03%]
药物诉讼中的法医分析发现大多数错误发生在常用的治疗和实践中
James T O&#x;Donnell,James J O&#x;Donnell,F Randy Vogenberg
James T O&#x;Donnell
In the complex setting of obstetrics and reproductive medicine, the medication-related injuries leading to the most litigation involve some of the most commonly used drugs, rather than the newer, more complicated therapies. The authors pres...
Meropenem-Vaborbactam (Vabomere™): Another Option for Carbapenem-Resistant Enterobacteriaceae [0.03%]
美罗培南-法硼巴坦(Vabomere?)):耐碳青霉烯类肠杆菌科细菌的又一治疗选择
Yuman Lee,Juliette Kim,Saralinh Trinh
Yuman Lee
Meropenem-Vaborbactam (Vabomere) for carbapenem-resistant Enterobacteriaceae.
Michele B Kaufman
Michele B Kaufman
Inbrija (levodopa inhalation powder) for oral inhalation for the treatment of "off" episodes in Parkinson's disease; Ultomiris (ravulizumab) injection for treating adults with paroxysmal nocturnal hemoglobinuria; and Yupelri (revefenacin) i...