Response of the IGF-I system to prolonged undernutrition and its involvement in somatic and skeletal muscle growth retardation in rats [0.03%]
长期营养不良对IGF-I系统的刺激及其在生长迟缓中的作用研究
T A Gautsch,S M Kandl,S M Donovan et al.
T A Gautsch et al.
We examined the response of the IGF-I system to prolonged undernutrition and its involvement in somatic and skeletal muscle growth retardation. Male rats were food-restricted to 50% of freely-fed controls (C) from birth to 120 days postpart...
Growth factor regulation of insulin-like growth factor (IGF) binding proteins (IGFBP) and preadipocyte differentiation in porcine stromal-vascular cell cultures [0.03%]
生长因子对猪血管基质细胞中胰岛素样生长因子结合蛋白的影响及前脂肪细胞的分化作用研究
R L Richardson,G J Hausman,J T Wright
R L Richardson
The influence of anti-IGF-1 and anti-transforming growth factor beta (TGF-beta) neutralizing antibodies on preadipocyte differentiation and secretion of IGFBPs was examined in serum free porcine stromal-vascular cultures. Cultures were stai...
Comparative Study
Growth, development, and aging : GDA. 1998 Spring-Summer;62(1-2):3-12. DOI: 1998
Localization and treatment of an oxidation-sensitive defect within the TCR-coupled signalling pathway that is associated with normal and premature immunologic aging [0.03%]
TCR相关信号转导通路中一个与正常及早发性免疫衰老相关的易氧化缺陷的定位和治疗
G F Weber,N M Mirza,E J Yunis et al.
G F Weber et al.
The age-dependent decline in the ability of T-cells to mount a proliferative response both to mitogens and to receptor ligation is due to an age-related defect in signal transduction, since functional expression of receptors displayed by ag...
Comparative Study
Growth, development, and aging : GDA. 1997 Fall-Winter;61(3-4):191-207. DOI: 1997
A M Bollen,K J McCulloch,S W Herring
A M Bollen
Our knowledge of total body bone resorption during growth is limited. The primary purpose of this study was to determine if a commercially available bone resorption assay, developed for measuring human bone resorption, could be used to meas...
Comparative Study
Growth, development, and aging : GDA. 1997 Fall-Winter;61(3-4):181-9. DOI: 1997
Body composition of inactivated growth hormone (oMt1a-oGH) transgenic mice: generation of an obese phenotype [0.03%]
灭活生长激素(oMt1a-oGH)转基因小鼠的体型构成及肥胖表型的产生
A M Oberbauer,J S Stern,P R Johnson et al.
A M Oberbauer et al.
The consequences of a 42 d exposure to elevated growth hormone (GH) on adipose tissue were assessed using the regulatable ovine metallothionein- ovine GH (oMt1a-oGH) transgene in male and female GH transgenic (TG) mice. Activation of transg...
Comparative Study
Growth, development, and aging : GDA. 1997 Fall-Winter;61(3-4):169-79. DOI: 1997
6R-L-erythro-5,6,7,8-tetrahydrobiopterin is involved in brain vulnerability of senescence-accelerated mouse during the processes of aging [0.03%]
6r-l-赤蝶长春花素参与衰弱型早老鼠脑衰老过程中的易损性
K Yoshimoto,T Yoshida,A Hirano et al.
K Yoshimoto et al.
The effects of age on the dopamine (DA) turnover and 6R-L-erythro-5,6,7,8-tetrahydrobiopterin (6R-BH4), a cofactor for monooxygenases, were investigated in the striatum and midbrain of the senescence accelerated mouse (SAM) at 6, 12 and 15 ...
Comparative Study
Growth, development, and aging : GDA. 1997 Fall-Winter;61(3-4):157-65. DOI: 1997
T Miyake,A M Cameron,B K Hall
T Miyake
We examined the relationships between litter size, embryonic growth, days of gestation, onset and duration of morphological stages and development of the first arch skeleton in three inbred strains of mice--C57BL/6, CBA/J and C3H/He. Detail...
Ontogenetic limb bone scaling in basic fibroblast growth factor (FGF-2) transgenic mice [0.03%]
骨形态发生蛋白2转基因小鼠肢体骨骼的发育规律研究
P S Lightfoot,R Swisher,J D Coffin et al.
P S Lightfoot et al.
Basic fibroblast growth factor (FGF-2) is a potent mitogen which is required for normal development, particularly the development of the skeletal system, where the inhibition of FGF binding to its receptor results in various skeletal malfor...
Late embryonic and early posthatch growth of heart and lung in White Leghorn lines of chickens [0.03%]
白来航鸡品系胚胎后期和出壳早期心脏及肺脏生长发育的比较研究
A Yang,P B Siegel
A Yang
Growth and development of heart and lungs were measured from day 15 of incubation to 25 days after hatch in lines of chickens that had undergone long-term selection for high (HAS) or low (LAS) antibody titers to sheep erythrocytes. A correl...