Microfluidic device using a gold pillar array and integrated electrodes for on-chip endothelial cell immobilization, direct RBC contact, and amperometric detection of nitric oxide [0.03%]
用于芯片上内皮细胞固定、直接红细胞接触和硝酸氮安培检测的集成电极金柱阵列微流控装置
Alexandra D Townsend,Randy S Sprague,R Scott Martin
Alexandra D Townsend
We describe a microfluidic device that can be used to detect interactions between red blood cells (RBCs) and endothelial cells using a gold pillar array (created by electrodeposition) and an integrated detection electrode. Endothelial cells...
Raja Ram Pandey,Hussain S Alshahrani,Sergiy Krylyuk et al.
Raja Ram Pandey et al.
Acetaminophen (APAP) is an antipyretic, analgesic agent, the overdose of which during medical treatment poses a risk for liver failure. Hence, it is important to develop methods to monitor physiological APAP levels to avoid APAP. Here, we r...
Multiplexed Electrochemical Cancer Diagnostics With Automated Microfluidics [0.03%]
自动化微流控的多重电化学生物芯片癌症诊断系统
Conan Mercer,Abby Jones,James F Rusling et al.
Conan Mercer et al.
Microfluidic platforms can lead to miniaturisation, increased throughput and reduced reagent consumption, particularly when the processes are automated. Here, a programmable microcontroller is used for automation of a microfluidic platform ...
Poly-L-lysine Coated Surfaces for Ultrasensitive Nucleic Acid Detection [0.03%]
聚L-赖氨酸包被表面的超灵敏核酸检测技术研究
Filiz Kuralay,Nilgün Dükar,Yaşar Bayramlı
Filiz Kuralay
Poly-L-lysine is one of the biocompatible polymers having amino and carboxyl groups in its structure. This attractive feature of poly-L-lysine makes it very convenient for bioactive molecule attachment. This study details the preparation of...
Magnetic Beads-Based Electrochemical Sensors Applied to the Detection and Quantification of Bioterrorism/Biohazard Agents [0.03%]
基于磁性微球的电化学传感器在生物恐怖主义/生物危害检测中的应用
María Pedrero,Susana Campuzano,José M Pingarrón
María Pedrero
Nowadays, detecting the presence of bioterrorism and biohazard agents in environmental and food samples is of great concern, due to their toxicity, and because many of them are prone to be used in terrorism attacks. The use of functionalize...
Performance of Amperometric Platinized-Nafion Based Gas Phase Sensor for Determining Nitric Oxide (NO) Levels in Exhaled Human Nasal Breath [0.03%]
基于铂-纳芬兰气相传感器测定人体呼出鼻腔气体中一氧化氮(NO)含量的性能研究
Joanna Zajda,Nicholas J Schmidt,Zheng Zheng et al.
Joanna Zajda et al.
Nitric oxide (NO) levels in exhaled breath are a non-invasive marker that can be used to diagnose various respiratory diseases and monitor a patient's response to given therapies. A portable and inexpensive device that can enable selective ...
The Use of a 3D-Printed Microfluidic Device and Pressure Mobilization for Integrating Capillary Electrophoresis with Electrochemical Detection [0.03%]
基于压力驱动的微流控芯片电泳电解检测集成接口及其应用研究
Melissa J Kimlinger,R Scott Martin
Melissa J Kimlinger
Capillary electrophoresis coupled with electrochemical detection can be a powerful analysis tool; however, previous methods developed to integrate these two techniques can often times be fragile and have alignment issues such that there are...
Carbon Nanohorn-Modified Carbon Fiber Microelectrodes for Dopamine Detection [0.03%]
用于多巴胺检测的碳纳米角修饰型碳纤维微电极
Pumidech Puthongkham,Cheng Yang,B Jill Venton
Pumidech Puthongkham
Carbon nanohorns (CNHs), closed cone-shaped cages of sp 2-hybridized carbons, are a promising nanomaterial to improve carbon-fiber microelectrode (CFME) dues to their high specific surface area and edge planes, but few studies have tested t...
Regional differences in dopamine release in the R6/2 mouse caudate putamen [0.03%]
R6/2小鼠尾状核多巴胺释放的区域性差异
Sam V Kaplan,Ryan A Limbocker,Beth Levant et al.
Sam V Kaplan et al.
Huntington's disease (HD) is a fatal neurodegenerative disorder that is characterized by degeneration of the striatum. Here, fast-scan cyclic voltammetry at carbon-fiber microelectrodes was used to uncover regional differences in dopamine (...
Enzyme Deposition by Polydimethylsiloxane Stamping for Biosensor Fabrication [0.03%]
聚二甲基硅氧烷印刻酶沉积法定制生物传感器
Bo Wang,Bonhye Koo,Harold G Monbouquette
Bo Wang
High-performance biosensors were fabricated by efficiently transferring enzyme onto Pt electrode surfaces using a polydimethylsiloxane (PDMS) stamp. Polypyrrole and Nafion were coated first on the electrode surface to act as permselective f...