Rethinking Transthyretin Amyloidosis: Insights from Taiwan Illuminate a Global Challenge [0.03%]
重新思考转甲状腺素蛋白淀粉样变性：来自台湾的见解照亮了全球挑战
Yu-Wen Cheng,Chun-Li Wang
Yu-Wen Cheng
The Relationship Between VO2 Max and Heart Rate Variability Parameters in Individuals with High Risk for Cardiovascular Disease [0.03%]
心血管疾病高危人群的最大摄氧量和心率变异性参数之间的关系
Selin Cilli Hayıroğlu,Mehmet Uzun
Selin Cilli Hayıroğlu
Objective: The purpose of this study was to evaluate the relationship between heart rate variability (HRV) parameters, classified into frequency and time domains, and maximal oxygen uptake (VO2 max) in individuals at high...
miR-138-5p Promotes HF in Rats by Reducing Histone Methylation in the Myd88 Promoter Region through Inhibition of EZH2 [0.03%]
miR-138-5p通过抑制EZH2降低MyD88启动子区域组蛋白甲基化诱导大鼠心脏肥厚
Ye Zhang,Weihui Lu
Ye Zhang
Objective: We aimed to investigate how microRNA-138-5p (miR-138-5p) promotes heart failure (HF) in rats by inhibiting enhancer of zeste homolog 2 (EZH2) and reducing histone methylation in the myeloid differentiation prim...
Comprehensive Assessment of Ventricular Remodeling Following Mitral Valve Repair: A Focus on Volume, Mass, and Relative Wall Thickness [0.03%]
二尖瓣修复术后的全面评估：以体积、质量及相对壁厚度为重点
Chih-Yao Chiang,Wei-Ting Lee,Shen-Che Lin et al.
Chih-Yao Chiang et al.
Background: Mitral valve repair facilitates ventricular reverse remodeling, inducing changes in geometry and mass. This study examined geometric normalization and mass regression following valve repair, and evaluated corr...
Multidisciplinary Approaches for Diagnosing Underrecognized Transthyretin Amyloidosis in Real-World Practice [0.03%]
真实世界实践中多学科方法诊断未被充分认识的转甲状腺素蛋白淀粉样变性的方法
Hao-Chih Chang,Ling Kuo,Tsyr-Yan Yu et al.
Hao-Chih Chang et al.
Background: Transthyretin amyloidosis (ATTR) is a rare but progressive disease. Its heterogeneous clinical presentation often leads to a delayed diagnosis. This study aimed to review the clinical manifestations of ATTR at...
The Mechanism of KLF4-Mediated NF-κB/NLRP3 Pathway Regulating Arteriovenous Fistula Dysfunction [0.03%]
KLF4介导的NF-κB/NLRP3信号通路调节动静脉内瘘功能不良的机制研究
Yuanyuan Wang,Jihong Deng,Jinping Tan et al.
Yuanyuan Wang et al.
Objective: Arteriovenous fistula (AVF) is the lifeline of maintenance hemodialysis (MHD), and AVF dysfunction is a major burden for MHD patients. It is important to modulate the vascular inflammatory response in pathologi...
Goal Attainment Rate in Secondary Prevention in Taiwan - A Chang Gung Research Database Study [0.03%]
台湾地区二级预防目标达成率-中国医药大学数据库研究
Tien-Yu Chen,Chia-Chen Wu,Yi-Ting Chen et al.
Tien-Yu Chen et al.
Background: Effective lipid control is essential in the secondary prevention of cardiovascular disease to reduce recurrent events. However, the low-density lipoprotein cholesterol (LDL-C) goal attainment rates among high-...
Murat Özmen,Ramazan Aslan,Onur Akgün et al.
Murat Özmen et al.
Atrial septal aneurysms (ASAs) are usually asymptomatic and discovered incidentally during routine cardiac imaging. While their exact prevalence is unclear, ASAs can be associated with structural heart defects (such as patent foramen ovale ...
Network Pharmacology & Validation of Dihydrotanshinone I's Regulation of HIF-1α via STAT3 in Cardiomyocytes [0.03%]
网络药理学及丹参素甲通过STAT3调节心肌细胞HIF-1α的验证研究
Jianxun Zhao,Xiaoling Zhang,Yefu Liu et al.
Jianxun Zhao et al.
This study investigates the molecular mechanisms underlying the cardioprotective effects of dihydrotanshinone I (DT). Bioinformatics analysis of proteomic data was applied to explore the broad regulatory effects of DT on cellular processes ...