[Occurrence status and treatment strategies of abnormal growth and development in children with methylmalonic acidemia] [0.03%]
甲基丙二酸血症患儿生长发育异常的现状及干预措施研究进展
Hai-Yan Wei,Dong-Xiao Li
Hai-Yan Wei
Abnormalities in growth and development in children with methylmalonic acidemia (MMA) have become a central challenge affecting prognosis. As a relatively common disorder of organic acid metabolism, MMA has a complex etiology and exhibits h...
[Interpretation of the "European consensus guidelines on the management of respiratory distress syndrome: 2025"] [0.03%]
"欧洲呼吸窘迫综合征管理共识指南（2025）解读"
Xiao-Qing Chen,David G Sweet,Yuan Shi
Xiao-Qing Chen
Neonatal respiratory distress syndrome (RDS) is a critical disease caused by pulmonary surfactant (PS) deficiency, leading to respiratory distress soon after birth. Comprehensive perinatal interventions can significantly improve outcomes. T...
[Advances in the role of miR-378a in skeletal muscle development and diseases] [0.03%]
miR-378a在肌肉发育和疾病中的作用研究进展
Zi-Ting Ding,Dan Lan
Zi-Ting Ding
MicroRNAs (miRNAs) are endogenous noncoding RNAs involved in post-transcriptional regulation. miR-378a is highly expressed in skeletal muscle and plays important roles in myogenesis, maintenance of muscle homeostasis, and disease progressio...
[Research progress on maternal factors influencing the risk of autism spectrum disorder in offspring from a gut-brain axis perspective] [0.03%]
从肠-脑轴角度探究母体因素对子代自闭症谱系障碍发病风险影响的研究进展
Hao-Bo Ding,Chuang Li,Shu-Li Wu
Hao-Bo Ding
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by core features of social communication deficits and repetitive, stereotyped behaviors. Maternal environmental factors during pregnancy are considered important ...
[Recent advances in individualized treatment for pediatric high-risk B-cell acute lymphoblastic leukemia] [0.03%]
[儿童高危B细胞急性淋巴细胞白血病个体化治疗新进展]
Yu-Qi Li,Ya-Jie Wang,Zeng-Zheng Li et al.
Yu-Qi Li et al.
B-cell acute lymphoblastic leukemia (B-ALL) is the most common hematologic malignancy in children. High-risk B-ALL, due to factors such as poor early treatment response and adverse genetic features, is prone to drug resistance and relapse, ...
Wei-Rui Wang,Wang Peng,Xiang-Rong Zheng
Wei-Rui Wang
Bronchial asthma (asthma) is the most common chronic inflammatory airway disease in children. Traditional pharmacotherapy achieves a disease control rate of less than 60%, and limitations such as poor treatment adherence and drug-related ad...
[Two cases of congenital myotonic dystrophy type 1 caused by DMPK gene variants] [0.03%]
[由DMPK基因变异所致的2例先天性肌强直性营养不良1型]
Xiao-Hong Wang,Chen-Hong Wang,Yan-Ping Xu et al.
Xiao-Hong Wang et al.
Patient 1 was a male neonate who, at 3 hours of life, presented with respiratory distress, hypotonia, and ventilator dependence. Genetic testing revealed a DMPK gene CTG repeat expansion (13/>83). Patient 2 was a male neonate who presented ...
[A case of Berry syndrome associated with SOX11-related Coffin-Siris syndrome type 9] [0.03%]
[九号科芬-萨里斯综合征（SOX11相关）合并贝瑞氏综合征一例]
Yuan Wang,Zhi Wang
Yuan Wang
A male infant was admitted to the neonatal intensive care unit for respiratory distress 12 minutes after preterm birth. Prenatal fetal echocardiography suggested transposition of the great arteries with an intact ventricular septum. Amnioce...
[Inhibition of ferroptosis by geniposide via activation of the SIRT3 signaling pathway to alleviate inflammatory injury in endothelial cells] [0.03%]
通过激活SIRT3信号通路抑制内皮细胞炎症损伤中的铁死亡作用机制研究
Wen-Ting Sun,Miao-Miao Zhao,Zhao-Ling Shi
Wen-Ting Sun
Objectives: To study the effect and mechanism of geniposide (GE) on lipopolysaccharide (LPS)-induced inflammatory injury in human coronary artery endothelial cells (HCAECs). ...
[Clinical and genetic characteristics of 165 children with salt-wasting 21-hydroxylase deficiency in Henan Province] [0.03%]
河南省165例盐耗损型21-羟化酶缺乏症患儿的临床及遗传特征分析
Hai-Hua Yang,Ai Huang,Yuan Li et al.
Hai-Hua Yang et al.
Objectives: To explore the clinical and genetic characteristics of children with salt-wasting (SW) 21-hydroxylase deficiency (21-OHD) in Henan Province. M...