Structure of desheptapeptide (B24-B30) insulin in a new crystal form [0.03%]
新型晶体中脱七肽(B24-B30)胰岛素的结构
S Bao,J Zhang,W Chang et al.
S Bao et al.
The structure of desheptapeptide (B24-B30) insulin (DHPI) in a new crystal form (form B) has been determined and refined to 0.2 nm resolution. The crystals were obtained under the same crystallization condition as previously reported crysta...
A prourokinase-RGDS chimera : Construction, expression and characterization [0.03%]
重组urokinase-RGDS嵌合体的构建、表达及性质表征研究
B Qian,Y Sun,Y Guo et al.
B Qian et al.
A tetrapeptide, RGDS, was inserted into proUK kringle domain G118-L119 by the construction of a mutant proUK-RGDS gene. The gene was expressed in the baculovirus expression system. Immunoaffinity chromatography was used to purify the chimer...
Phytogeny of genusGlossina (Diptera:Glossinidae) according to ITS2 sequences [0.03%]
基于ITS2序列的采采蝇属(Glossina)的系统发生关系研究
X Chen,S Li,C Li et al.
X Chen et al.
The flies of genusGlossina (Diptera: Glossinidae) are an important vector of African trypanosomiases which cause diseases in humans and animals. The ribosomal DNA Internal Transcribed Spacer-2 (ITS-2) region sequences from differentGlossina...
Activation of Na(+) /H (+) exchange on rat preadipocyte plasma membrane and its role in cell proliferation and differentiation [0.03%]
大鼠前脂肪细胞膜Na+/H+交换的激活及其在增殖和分化中的作用
Q Chen,X Li,Z Lu et al.
Q Chen et al.
Anin vitro cultured rat perirenal preadipocyte (PA) was established as a model system to investigate the role of the intracellular pH (pHi) and of the Na(+) /H(+) exchanger during PA proliferation and differentiation. pH sensitive probe, 2'...
Assembly and structure of neurofilaments isolated from bovine spinal cord [0.03%]
由牛脊髓中分离的神经丝的装量及其结构
X Tong,J Chen,J Liu et al.
X Tong et al.
Neurofilaments (NFs) are neuron-specific intermediate filaments. The NFs were isolated from bovine spinal cord by differential centrifugation. The NFs were detected with electron microscopy and scanning tunneling microscopy (STM). Under STM...
H Zhang,S Song,Z Lin
H Zhang
Thirty-seven sets of crystallographic enzyme data were selected from Protein Data Bank (PDB, 1995). The average temperature factors (B) of the critical residues at the active site and the whole molecule of those enzymes were calculated resp...
In vivo distribution and gene expression of genetically modified hepatocytes after intrasplenic transplantation [0.03%]
基因改造肝细胞脾内移植后的体内分布及基因表达
W Zhang,X Cao,X Huang et al.
W Zhang et al.
To investigate the feasibility and efficacy of liver gene therapy mediated by intrasplenic transplantation of genetically modified hepatocytes, the normal mouse liver cell line BNL CL. 2 cells were introduced with Neo-resistant (NeoR) gene ...
Pharmacokinetics of recombinant human interleukin-3 in rhesus monkeys [0.03%]
重组人白细胞介素-3在恒河猴体内的药代动力学研究
Z Tang,X Liu,M Tu
Z Tang
Concentration-time profiles of(125)I-labeled recombinant human interleukin-3 ((125)1rhIL-3) were determined by reverse phase high performance liquid chromatography (RHPLC) after intravenous and subcutaneous administration of the drug in 16 ...
Enhanced antitumor effects of tumor antigen-pulsed dendritic cells by their transfection with GM-CSF gene [0.03%]
GM-CSF基因转染增强肿瘤抗原脉冲树突细胞的抗肿瘤效应
X Cao,W Zhang,S Ma et al.
X Cao et al.
To investigate the biological characterization and antitumor activities of GM-CSF gene-transfected dendritic cells, the splenic dendritic cells were infected with GM-CSF recombinant replication-deficient adenovirusesin vitro. Their enhanced...
Atypical neuroleptic properties ofl-stepholidine : Electrophysiological and behavioral studies [0.03%]
L-Steppogenine的非典型神经阻滞特性：电生理和行为学研究
X Zhang,B Sun,G Jin
X Zhang
Intravenous administration ofl-stepholidine (SPD), a dopamine (DA) receptor antagonist, increased the firing rate of DA neurons located in the ventral tegmental area (VTA) and substantia nigra pars compacta (SNC) in both anaesthetized and p...