[Single-cell sequencing reveals the temporal expression characteristics of key molecules related to tooth agenesis and dental hard tissues in mouse molars] [0.03%]
单细胞测序揭示小鼠磨牙先天缺牙及矿化组织关键分子的时间表达特征
W Guo,X P Wang,T Y Su et al.
W Guo et al.
Objective: Single-cell RNA-sequencing (scRNA-seq) technologies was used to analyze the temporal expression characteristics of molecules associated with congenital tooth agenesis and dental hard tissues during mouse molar development, in ord...
[Association analysis of methylation-related genes TET1 and NSD1 with non-syndromic orofacial clefts] [0.03%]
TET1和NSD1甲基化相关基因与无综合征唇腭裂的关联分析
S X Jia,Y You,B Shi et al.
S X Jia et al.
Objective: This study aims to preliminarily investigate the role of methylation in the epigenetic regulation of the pathogenesis of non-syndromic orofacial clefts (NSOC), to address the gaps in previous explorations of susceptibility genes ...
[Phenome-wide Mendelian randomization identifies causal exposures for nonsyndromic cleft lip with or without cleft palate] [0.03%]
全表型组孟德尔随机化识别孤立性唇裂伴或不伴腭裂的致病暴露因素
S Lou,C Y Xing,Y C Pan
S Lou
Objective: To systematically investigate the causal effects of exposure factors on nonsyndromic cleft lip with or without cleft palate (NSCL/P) using a phenome-wide Mendelian randomization (MR-PheWAS) framework and identify pleiotropic loci...
X H Duan
X H Duan
The low prevalence and complex clinical characteristics of oral rare diseases make their diagnosis and treatment difficult in clinical practice. The publication of "The first edition of oral rare diseases list" in 2020 provides the importan...
J Liang,Z Bian
J Liang
This study provides a comprehensive review of the development and achievements in the field of oral genetic disorders research in China. Since the 1950s, Chinese scholars have progressed from epidemiological surveys to the elucidation of mo...
Y L Song
Y L Song
Oral rare diseases are a group of disorders characterized by distinct oral and craniofacial manifestations. These conditions are featured by low prevalence, high genetic and clinical heterogeneity, and great challenges in diagnosis and trea...
S Yu,H Qiao,X Zhang
S Yu
Rare diseases have become an issue of public health concern globally. In China, two rare disease lists have been released officially in 2018 and 2023, respectively. However, due to its importance in research, clinical management , therapeut...
[Advances in the application of photoacoustic imaging technology for oral disease diagnosis] [0.03%]
[光声成像技术在口腔疾病诊断中应用进展]
L L Cheng,Y Zhang,W Y Huang et al.
L L Cheng et al.
Photoacoustic imaging (PAI), an emerging hybrid imaging modality, integrates the high spatial resolution of optical imaging with the deep-tissue imaging capability of ultrasound. Emerging evidence from recent studies in dental medicine has ...
Sihan Yu,Liwei Zheng,Mian Wan
Sihan Yu
（microplastics），、，，。。，，，。，A，、，。，。，。. 微塑料暴露对机体矿化组织发育与形成的影响于斯涵1 郑黎薇1 万冕21四川大学华...
[Research progress on the effect of root canal therapy on vertical root fracture] [0.03%]
根管治疗与垂直根裂关系的研究进展
D Wan,R T Shi
D Wan
Vertical root fracture (VRF) often occurs in endodontically treated teeth. Root canal therapy (RCT) requires removal of part of the dentin, which affects the microhardness and elastic modulus of dentine, induces dentin microcracks, and incr...