A Comparative Analysis of Generic Drug Assessment and Regulatory Approval in the USA, Europe and India [0.03%]
美国、欧洲和印度仿制药评审及上市审批比较分析
Bhoomi D Patel,Shailesh P Suthar,Arman M Mansuri et al.
Bhoomi D Patel et al.
The Abbreviated New Drug Application (ANDA) is used for the regulatory submission of generic drugs, which are pharmaceutical equivalents to brand-name drugs and distributed without patent protection. Different countries have their own regul...
Mechanistic Insights into Tau Protein-Mediated Regulation of Oxidative Stress [0.03%]
tau蛋白介导的氧化应激调节机制初探
Pranshul Sethi,Ronald Darwin C,Ramakrishna Borra et al.
Pranshul Sethi et al.
Abnormal hyperphosphorylation and microtubule-associated protein tau aggregation development in the brain are characteristics of neurodegenerative diseases referred to as tauopathies, which include Alzheimer's disease (AD). The current revi...
In Vitro Cytotoxicity and Pharmacokinetic Study for Bosutinib Solid Lipid Nanoparticles [0.03%]
博舒替尼固体脂质纳米粒的体外细胞毒性和药动学研究
Baddela Nagaiah,S Nirmala
Baddela Nagaiah
Objective: Bosutinib (BST) is a Biopharmaceutics Classification System Class II drug having very low solubility and high permeability. Low aqueous solubility and poor dissolution of BST lead to poor bioavailability, Thus,...
Unveiling the Therapeutic Potential and Conservation Strategies for Rare and Endangered Medicinal Plants in Traditional Chinese Medicine: A Comprehensive Review [0.03%]
揭示传统中医稀有濒危药用植物的治疗潜力及保护策略：全面综述
Sonali Rastogi,Ritu Verma,Rajapandi Raju et al.
Sonali Rastogi et al.
Introduction: Incorporating rare and threatened healing plants from Traditional Chinese Medicine (TCM) into modern medicine is a hopeful way to expand treatment choices and encourage the long-term use of plant resources. ...
Design and Development of Propranolol HCl Fast Dissolving Tablets by Using Isolated Mucilage of Salvia Hispanica for the Treatment of Hypertension by Using DoE tools [0.03%]
响应面法优化大理苍耳子黏蛋白普朗尼洛尔盐酸盐快速溶解片的制备工艺及稳定性研究
Nandhini J,B Anandhi,Soumya Stuti Patnaik et al.
Nandhini J et al.
The main issue with Hypertension therapy is quick commencement of effect. The creation of suitable dose forms may help address the issue of medications having a delayed beginning of effect. Oral Antihypertensive medication treatment is best...
Preparation of Allium Cepa Peel Extract-mediated Silver Nanoparticles: A Hair Dye Formulation [0.03%]
基于洋葱皮提取物的银纳米颗粒的制备及护发剂配方研究
B Rama,Srujana K,K Sudhamani et al.
B Rama et al.
The burgeoning field of nanotechnology has ushered in innovative Novel drug delivery systems (NDDS) that enhance the efficacy, safety, and patient compliance of pharmaceutical treatments. This study explores the synthesis and application of...
Siva Prasad Sagili,P Phani Deepika,Eswaramma Pavuluri et al.
Siva Prasad Sagili et al.
Background: Following the COVID-19 pandemic, microvascular and macrovascular thrombotic problems emerged that required anticoagulants. Apixaban (RN) is a factor Xa inhibitor that treats deep vein thrombosis and the two fo...
Evaluation of Antidepresant Activity and Phytochemical Screening of Plant Cordia Dichotoma [0.03%]
采用药理筛选方法评价 Cordia dichotoma 的抗抑郁活性及植物化学成分筛查研究
Puneet Sudan,Venkateswara Rao Jallepalli,B Ramu et al.
Puneet Sudan et al.
Introduction: The traditional medicinal system of India, Ayurveda, has mentioned Cordia Dichotoma as a potential treatment for various ailments. In the current research, the extracts of Cordia Dichotoma was examined to ev...
Santhosh Illendula,Shailesh Sharma
Santhosh Illendula
A simple, Accurate, precise method was developed for the estimation of the Lorlatinib in API form and Marketed pharmaceutical dosage form by RP-HPLC. Chromatogram was run through Hypersil C18 (4.6mm×150mm, 5µm) Particle size Column and Mo...
Statistical Design Approach for the Formulation And Optimization of Nanosponges Using Poorly Water-soluble Candidate [0.03%]
基于统计设计的难溶性药物纳米海绵制剂的研究与优化
Ritu Verma,Pranshul Sethi,Sonali Rastogi et al.
Ritu Verma et al.
Background and objectives: Nanosponges are one of the most innovative ways to use the newest developments in nanodrugs delivery. Nanosponges can catch drugs that dissolve in water or ones that don't. This work uses statis...