Titanium Nanoparticles in Theranostics: A Multifunctional Platform for Targeted Therapy and Advanced Diagnostics [0.03%]
用于靶向治疗和先进诊断的钛基纳米药物多功能平台研究进展
Sakshi Dnyaneshwar Khatale,Pravin Rangnath Dighe
Sakshi Dnyaneshwar Khatale
Aim: To assess the theranostic potential of titanium nanoparticles (TiNPs), especially titanium dioxide nanoclusters, by assessing their distinct physicochemical characteristics and uses in biomedical domains as gene tran...
Degradation Studies and Method Development and Validation of Lanadelumab Using UV Detector in RP-HPLC [0.03%]
用于RP-HPLC紫外检测器的兰尼单抗降解研究及方法学开发和验证
S Marakatham,Meruva Sathish Kumar,A Kavya et al.
S Marakatham et al.
The RP-HPLC methodology was used to establish a straightforward, accurate, and precise method for estimating Lanadelumab. The following chromatographic conditions were used: 5. Mobile phase: 0.1% OPA buffer: Acetonitrile in a ratio of 65:35...
Beyond Hemoglobin: A Review of Hemocyanin and the Biology of Purple Blood [0.03%]
超越血红蛋白：血蓝蛋白和紫血生物学的综述
Gaurav Tiwari,Ruchi Tiwari
Gaurav Tiwari
Hemocyanin is dissolved freely in hemolymph, the invertebrate blood substitute, in contrast to haemoglobin, which is encased in red blood cells. When oxygenated, this pigment gives mollusc and arthropod blood its characteristic blue or purp...
Apexa M Shah
Apexa M Shah
Poorly soluble small compounds pose challenges in drug formulation due to low solubility, bioavailability, and therapeutic efficacy. These compounds often struggle to effectively target the disease due to their limited solubility. A large p...
Pharmaceutical Cocrystals: A Review on Design, Preparation, Application and Challenges [0.03%]
药物共晶研究：设计、制备、应用及挑战综述
Suvarna Jagannath Shelke,Dhanashri Haushiram Bhangare,Mayuri Deepak Patil
Suvarna Jagannath Shelke
Pharmaceutical cocrystals have emerged as a transformative approach in drug development, enhancing the physicochemical properties of active pharmaceutical ingredients (APIs) such as solubility, bioavailability, stability, and dissolution ra...
Acetylcholinesterase Inhibitor-Based Nose‑to‑Brain Delivery of Donepezil‑Loaded Lipid Nanoemulsion for Alzheimer's Therapy [0.03%]
基于乙酰胆碱酯酶抑制剂的载多奈哌齐脂质纳米乳鼻-脑输送系统用于阿尔茨海默病治疗
Chandan Mohanty,Mahendrakumar R Dubey,Saswati Panigrahi et al.
Chandan Mohanty et al.
Intranasal delivery offers a promising route for direct drug transport to the central nervous system, bypassing the blood-brain barrier and improving therapeutic outcomes in neurodegenerative diseases like Alzheimer's disease. Donepezil, a ...
CD3-Bispecific Monoclonal Antibodies: A Novel Therapeutic Approach for Complex and Multifactorial Diseases [0.03%]
针对复杂且多因素疾病的新型疗法——双特异性单克隆抗体_cd3分子
Shubham Singh,Sanjesh Rathi,Sakshi Singh et al.
Shubham Singh et al.
Monoclonal antibodies (mAbs) have witnessed significant advancements in recent years, offering promising therapeutic options for the management of complex and multifactorial diseases. Despite their success, conventional mAbs exhibit limitat...
Cancer Research in the 21st Century: Recent Advances and Future Perspectives [0.03%]
二十一世纪的癌症研究：近期进展与未来展望
Vrushali P Patole,Nirmala V Shinde,Siddhi M Chandak et al.
Vrushali P Patole et al.
Introduction: Cancer remains a major global health concern, accounting for nearly 10 million deaths annually. Despite its complexity and heterogeneity, significant advancements in cancer research over the past two decades...
Golden Flaxseed (Linum Usitatissimum): Unveiling Its Botanical Marvels, Therapeutic Potentials, and Nanoscale Applications [0.03%]
金亚麻（林埃斯佩朗迪）：揭开其药用潜力、植物学奇观及纳米应用之谜
Nirmala V Shinde,Nikita S Sahane,Sachin K Bhosale et al.
Nirmala V Shinde et al.
Flax seeds, scientifically known as Linum usitatissimum, are nutrient-rich seeds with omega-3 fatty acids, lignans, and fiber. They offer diverse health benefits including cholesterol reduction, cardiovascular support, anti-inflammatory pro...
A Pharmacological Study of Shirisharishta and Its Antihistaminic Effects in Guinea Pigs with Reference to Urticaria [0.03%]
药理学研究：希哩哩食纳对豚鼠荨麻疹的抗组胺作用研究
Monarani Chaurasia,Praveena P Nair,Aparna Saxena
Monarani Chaurasia
The effect of Shirisharishta on histamine-induced bronchospasm in guinea pigs was evaluated in this study. Guinea pigs were placed in a histamine chamber, and an aerosol of 0.5% histamine was introduced using a compressor and nebulizer. The...