Drug-drug Interaction between Pravastatin and Gemfibrozil (Antihyperlipidemic) with Gliclazide (Antidiabetic) in Rats [0.03%]
普伐他汀和吉非罗齐(抗高脂血症)与格列美脲(降糖药)在大鼠之间的药物相互作用研究
Cm Sultanpur,S Satyanarayana,Ns Reddy et al.
Cm Sultanpur et al.
Diabetes mellitus is a condition of increased blood glucose level in the body. Antihyperlipidemic drugs like statins and fibrates are widely used for prophylactic treatment in dyslipideamia and atherosclerosis. Diabetic dislipidemia exists ...
Possible role of hydrogen sulfide in insulin secretion and in development of insulin resistance [0.03%]
氢硫酸可能在胰岛素分泌和胰岛素抵抗发展中的作用
Ma Patel,Gb Shah
Ma Patel
H(2)S has been proposed as physiological important molecule. It is considered as first endogenous gaseous K(+) channel opener. K(+) ATP channel activity is mainly responsible for insulin secretion. K(+)ATP channel opening of β cells leads ...
Glucagon Secreting Cells Responds to Insulin Secretion In vitro Using Immunocytochemistry [0.03%]
应用免疫细胞化学在体外研究胰岛素分泌对胰高糖素分泌的影响
Mk Aswar,Um Aswar,Nk Subhedar
Mk Aswar
In the present study, pancreas of rats were dissected and transferred to HEPES buffer (25 mM, pH 7.4). The control tissue pieces were kept in culture medium for one hour and the treated tissues were kept in same medium for 30 minutes and in...
Antioxidant, Antinociceptive and Anti-inflammatory Activities of Ethanolic Extract of Leaves of Alocasia indica (Schott.) [0.03%]
Alocasia indica（Schott.）叶乙醇提取物的抗氧化、镇痛和抗炎作用
Wa Mulla,Sb Kuchekar,Vs Thorat et al.
Wa Mulla et al.
Extracts obtained from the leaves of various Alocasia species have been used in India as folk remedy for the treatment of various inflammatory ailments including rheumatism and bruise. The ethanolic extract of leaves of Alocasia indica Scho...
Aqueous Extract of Ficus bengalensis Linn. Bark for Inflammatory Bowel Disease [0.03%]
圣加尔榕树皮的水提物可治疗炎症性肠病
Ma Patel,Pk Patel,Mb Patel
Ma Patel
The present study was designed to evaluate the effects of aqueous extract of Ficus bengalensis Linn. bark (AEFB) on inflammatory bowel disease (IBD). Effects of AEFB were studied on 2, 4, 6-trinitrobenzenesulfonic acid (TNBS, 0.25 ml 120 mg...
Formulation and evaluation of extended-release solid dispersion of metformin hydrochloride [0.03%]
盐酸二甲双胍缓释固态分散体制备及评价
Sa Patil,Bs Kuchekar,Ar Chabukswar et al.
Sa Patil et al.
The purpose of this research was to formulate and characterize solid dispersion (SD) of metformin hydrochloride using methocel K100M as the carrier by the solvent evaporation and cogrinding method. The influence of drug polymer ratio on dru...
Studies on In situ Hydrogel: A Smart Way for Safe and Sustained Ocular Drug Delivery [0.03%]
原位水凝胶的眼用给药研究：一种安全、长效的给药方式
Dh Shastri,Ld Patel,Rk Parikh
Dh Shastri
The present work describes the formulation development of ophthalmic in situ gelling system using thermo-reversible gelling polymer, i.e. Pluronic F 127 (PF127). Because of high concentration (20 to 25%w/v) of this polymer required for in s...
Conflict of interest in peer-reviewed medical journals: the world association of medical editors position on a challenging problem [0.03%]
论医学期刊同行评审中的利益冲突问题世界医学编辑协会关于一个亟待解决的问题的立场声明
L E Ferris,R H Fletcher
L E Ferris
Dronedarone: a new therapeutic alternative for cardiac arrhythmias [0.03%]
心房颤动患者的非华法林抗凝疗法：疗效与安全性的比较研究——来自香浓专家圆桌会议的报告
A Upaganlawar,H Gandhi,R Balaraman
A Upaganlawar
Revisiting Metformin: Annual Vitamin B12 Supplementation may become Mandatory with Long-Term Metformin Use [0.03%]
二甲双胍的老问题：长期服用可能需要定期补充维生素B12
R Mahajan,K Gupta
R Mahajan
Monitoring of adverse drug reactions of a drug is a continuous process and runs through-out the life of a drug. Many rare adverse effects of a drug are documented after years of use; when a single case (signal generation) is reported leadin...