Leucine125Valine (Leu125Val) Gene Polymorphism of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) and Myocardial Infarction in Indian Population [0.03%]
印度人群血小板内皮细胞粘附分子-1（PECAM-1）第125位的亮氨酸/缬氨酸基因多态性与心肌梗死的关系研究
Kavita K Shalia,Manoj R Mashru,Surendra L Soneji et al.
Kavita K Shalia et al.
Platelet-endothelial cell adhesion molecule-1 (PECAM-1) has role in atherosclerotic plaque development as well as in thrombosis leading to myocardial infarction (MI). Present study was aimed to analyse the association of PECAM-1 Leu125Val g...
Polymorphisms of CYP1A1, GSTM1 and GSTT1 Loci as the Genetic Predispositions of Oral Cancers and Other Oral Pathologies: Tobacco and Alcohol as Risk Modifiers [0.03%]
CYP1A1，GSTM1和GSTT1基因多态性在口腔癌及其他口腔疾病遗传易感性中的作用：烟草和酒精使用作为危险因素的作用分析
Sumana Chatterjee,Soujatya Dhar,Bani Sengupta et al.
Sumana Chatterjee et al.
Polycyclic aromatic hydrocarbons of tobacco require activation by phase I enzymes, such as cytochrome-P4501A1 (CYP1A1) to become an ultimate carcinogen, which are subjected to detoxification by phase II enzymes, especially glutathione S-tra...
Matrix metalloproteinases and their inhibitors: correlation with invasion and metastasis in oral cancer [0.03%]
基质金属蛋白酶及其抑制物与口腔癌侵袭和转移的关系
Ragini D Singh,N Haridas,Jayendra B Patel et al.
Ragini D Singh et al.
Matrix metalloproteinases (MMPs) have been implicated in invasion and metastasis of various malignancies. The study evaluated a comprehensive profile of MMP-2 and MMP-9 and their inhibitors, tissue inhibitor of metalloproteinases-2 (TIMP-2)...
Oxidatively Damaged DNA: A Possible Antigenic Stimulus for Cancer Autoantibodies [0.03%]
氧化损伤的DNA：癌症自身抗体的潜在抗原刺激因素
Saba Khan,Moinuddin,Roshan Alam et al.
Saba Khan et al.
Reactive oxygen species (ROS) are cytotoxic at higher concentration resulting in cell death, mutations, chromosomal aberrations or carcinogenesis. In this study DNA was modified by singlet oxygen and superoxide anion radicals generated by i...
Reconvene and reconnect the antioxidant hypothesis in human health and disease [0.03%]
重新审视和建立抗氧化剂在人类健康与疾病中的作用假说
P P Singh,Anu Chandra,Farzana Mahdi et al.
P P Singh et al.
The antioxidants are essential molecules in human system but are not miracle molecules. They are neither performance enhancers nor can prevent or cure diseases when taken in excess. Their supplemental value is debateable. In fact, many high...