The effect of modification of DNA interference on myostatin gene expression in mice [0.03%]
DNA干扰修饰对小鼠肌肉生长抑制素基因表达影响的研究
Mitra Riasi,Sina Mozaffari-Jovin,Ali Javadmanesh
Mitra Riasi
Myostatin is a known negative regulator of muscle tissue growth. Thus, an inhibitor of myostatin may be therapeutically useful as an anabolic agent for the muscle tissue. A promising gene-silencing approach for gene therapy is DNA interfere...
Durgadas P Kasbekar
Durgadas P Kasbekar
In the fruit fly Drosophila melanogaster, circadian rhythm was disrupted when the inner nuclear membrane protein lamin B receptor (LBR) was depleted from its clock neurons (Proc. Natl. Acad. Sci. USA 118, e2019756118. 2021; https://doi.org/...
Genetic diversity analysis of volunteer wheat based on SSR markers [0.03%]
基于SSR标记的 volunteers的小麦遗传多样性分析
Wangcang Su,Hongle Xu,Lanlan Sun et al.
Wangcang Su et al.
Volunteer wheat is a kind of wheat with weed characteristics, distributed widely in the main wheat-producing areas of China. It seriously damages the yield and quality of cultivated wheat. To study the genetic diversity and population struc...
Why are you hitting yourself? Whole-exome sequencing diagnosis of monogenic autoimmunity [0.03%]
为什么你打自己？单基因自身免疫病的外显子组诊断
Lina M Castano-Jaramillo,Francisco Rivas Larrauri,Selma C Scheffler-Mendoza et al.
Lina M Castano-Jaramillo et al.
Inborn errors of immunity may present with autoimmunity and autoinflammation as hallmark clinical manifestations. We aimed to identify the potential monogenic causes of autoimmune disorders in 26 patients from a pediatric reference hospital...
olf413, a putative octopamine biosynthesis pathway gene is required for negative geotactic motor function in Drosophila melanogaster [0.03%]
拟神经递质八胺生物合成途径基因olf413是负重力驱动运动所必需的
Ravindrakumar Ramya,Venkatanarayanasetty Baragur Shyamala
Ravindrakumar Ramya
Olf413 gene annotated as CG12673 in the genome of Drosophila melanogaster has been predicted to code for a protein with putative function in octopamine biosynthesis. The expression pattern and the biological function of the gene awaits inve...
Exploring the influences of geographical variation on sequence signatures in the human gut microbiome [0.03%]
地理差异对人类肠道微生物组序列特征影响的分析
Gauraw Kumar,Punyasloke Bhadury
Gauraw Kumar
Geography shapes the structure and function of human gut microbiomes. In this study, we have explored the available human gut microbiome 16S rRNA sequence datasets of cohorts representing large geographical gradients. The 16S rRNA sequences...
Yonghong Xie,Yunmin Wei,Rongrong Han et al.
Yonghong Xie et al.
The formate dehydrogenase (FDH) is regarded as a universal stress protein involved in various plant abiotic stress responses. This study aims to ascertain GmFDH function in conferring tolerance to aluminum (Al) stress. The bioinformatics an...
AICRF: ancestry inference of admixed population with deep conditional random field [0.03%]
具有深度条件随机场的混合体祖源推断(AICRF)
Farhad Alizadeh,Hamid Jazayeriy,Omid Jazayeri et al.
Farhad Alizadeh et al.
Ancestry inference of admixed populations is an important issue in anthropology and studies of gene discovery, and characterization. Usually, local ancestor inference (LAI) methods use fixed-length windows to divide chromosomes into smaller...
David Curtis
David Curtis
Modern genetics research increasingly reveals that what is commonly termed Mendelian genetics occurs rarely in nature, especially with regard to the effects that genetic variation exerts on human characteristics. It has been argued that an ...
Serum exosomal hsa_circRNA_0001842 is the potential biomarker for diagnosing lower limb vascular disease in type 2 diabetes mellitus [0.03%]
外泌体hsa_circRNA_0001842可作为2型糖尿病下肢血管病变诊断的潜在标志物
Qian-Qian Liu,Xing-Hui Liu,Hai-Ming Wang et al.
Qian-Qian Liu et al.
This study aimed to identify the potential circular RNAs (circRNAs) in exosomes isolated from serum as biomarkers of lower limb vascular disease (LLVD) in patients with type 2 diabetes mellitus (T2DM). This research collected circRNAs from ...