Panmictic stock structure of milkfish (Chanos chanos,Forssål 1775) from Indian waters determined using mtDNA marker [0.03%]
基于线粒体DNA研究印度海域牛奶鱼种群遗传结构
Divya Merin Jose,P R Divya,Kuldeep K Lal
Divya Merin Jose
Milkfish (Chanos chanos) belongs to the family Chanidae and it is a potential candidate species for aquaculture with the best biological characteristics. This study investigates the genetic diversity and population structure of C. chanos al...
Arginase deficiency in Bulgaria: first cases and potential endemic region for the disorder [0.03%]
保加利亚的精氨酶缺乏症：首两例及该病的潜在地方性发病区域
Slavena Atemin,Tihomir Todorov,Ivan Tourtourikov et al.
Slavena Atemin et al.
Arginase deficiency is an autosomal recessive urea cycle disorder caused by pathogenic variants in the ARG1 gene. The clinical features of the disease include spasticity, tremour, ataxia, hypotonia, microcephaly and seizures. Growth delay c...
Mysteries in our genome [0.03%]
基因组里的未解之谜
Durgadas P Kasbekar
Durgadas P Kasbekar
Editorial
Journal of genetics. 2023:102:1. DOI: 2023
EMX2OS targeting IGF2BP1 represses Wilms' tumour stemness,epithelial-mesenchymal transition and metastasis [0.03%]
EMX2OS通过靶向IGF2BP1抑制Wilm's肿瘤干细胞特性、上皮间质转化及转移能力
Hong-Mei Zhang,Ming-Yu Cui,Zhi-Hong Chen
Hong-Mei Zhang
Wilms' tumour (WT) is the most typical type of renal tumour in children, which has a poor prognosis and high recurrence rate. This study explored whether lncRNA EMX2 opposite strand / antisense RNA (EMX2OS) modulated the stemness, epithelia...
LncRNA TTN-AS1 exacerbates extracellular matrix accumulation via miR-493-3p/FOXP2 axis in diabetic nephropathy [0.03%]
长链非编码RNA TTN-AS1通过miR-493-3p/FOXP2轴促进糖尿病肾病中细胞外基质蓄积
Lin Jia,Wenzhe Wang,Hui Liu et al.
Lin Jia et al.
Diabetic nephropathy (DN), a common cause of chronic renal failure and end-stage renal disease, leads to a high mortality. However, the role of TTN-AS1 in extracellular matrix (ECM) accumulation during DN remains unclear. In our study, TTN-...
Buket Cakmak Guner,Elif Karlik,Nermin Gozukirmizi
Buket Cakmak Guner
Evolution is unaimed changes in time that a genome is shaped by a collection of random mutations, recombination, integrations, and reorganizations. Transposable elements (TEs) are mobile fragments representing a major portion of most eukary...
A time-calibrated mitogenomic phylogeny suggests that Korean Hyalessa fuscata is a bridge between Chinese and Japanese H. maculaticollis [0.03%]
基于线粒体基因组构建的时间校正系统发育树表明韩国齿唇姬鼠(Hyalessa fuscata)是中华齿唇姬鼠和日本齿唇姬鼠的桥梁物种
Hoa Quynh Nguyen,Phuong-Thao Ho,Sungsik Kong et al.
Hoa Quynh Nguyen et al.
The cicada species, Hyalessa fuscata and H. maculaticollis(Hemiptera: Cicadidae), share numerous morphological characters, and their status as distinct species remains controversial. We reconstructed a phylogeny based on two new mitogenomes...
Population genetic structure and evolutionary demographic patterns of Phrynoderma karaavali, an edible frog species of Kerala, India [0.03%]
印度喀拉拉邦可食用蛙类Phrynoderma karaavali的群体遗传结构及进化人口动态模式
V S Anoop,Sanil George
V S Anoop
Trade and collection of edible frogs are banned in India. We used mitochondrial (16 and 12S DNA) and nuclear gene (Rag-1 and Rhodopsin) sequences to examine the population genetic and demographic structure of an edible frog species, Phrynod...
Exome sequencing and microarray identified a novel large exonic deletion in SYT2 gene in an ultra-rare case with recessive CMS type 7 [0.03%]
外显子组测序和微阵列检测到SYT2基因的新型大型外显子缺失罕见遗传性CMS7型病例中发现SYT2基因的大片段外显子缺失
C P Ravi Kumar,Parag M Tamhankar,Radhika Manohar et al.
C P Ravi Kumar et al.
Congenital myasthenic syndromes (CMSs) are a diverse group of diseases that have an underlying defect in transmission of signals from nerve cells to muscles that lead to muscular weakness. A 13-year-old male child born of consanguineous par...
Case Reports
Journal of genetics. 2023:102:7. DOI: 2023
CircHIPK3 promotes proliferation and metastasis of villous trophoblasts through miR-30a-3p/Wnt2 axis [0.03%]
环状HIPK3通过miR-30a-3p/Wnt2轴促进绒毛滋养细胞的增殖和转移
Shuhong Li,Ning Li,Bing Li et al.
Shuhong Li et al.
The aim of this paper was to explore the role and mechanism of circHIPK3 in unexplained recurrent spontaneous abortion (URSA). The expression of circHIPK3 and miR-30a-3p mRNA in URSA villous tissues was detected by quantitative polymerase c...