Dual effect of methylene-tetrahydrofolate reductase and angiotensinconverting enzyme gene polymorphisms on the risk of acute ischemic stroke [0.03%]
亚甲基四氢叶酸还原酶和血管紧张素转化酶基因多态性对急性缺血性脑卒中发病危险的联合作用
Nevin Karakus,Serbulent Yigit,Nursah Basol et al.
Nevin Karakus et al.
Ischemic stroke, a prevalent neurological disease, is the major reason of serious disability and death worldwide. Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms increase homocysteine levels which also raise the risk of vascu...
Identification of fertility restorers for A2 cytoplasm-based CGMS lines and development of short duration hybrids in pigeonpea (Cajanus cajan(L.) Millsp.) [0.03%]
鉴定赛姆迪卡纳系列A2型胞质不育保持系及恢复系并利用其快速开发杂交品种
M S Ranjani,P Jayamani
M S Ranjani
Pigeonpea is the second most important legume crop grown in India after chickpea. India is the largest producer of pigeonpea in the world. However, the productivity of pigeonpea in India remains stagnant over the years. The productivity of ...
Association of ABCA1 R219K polymorphism and telomere length in a Chinese rural population: possible linking to systemic inflammation [0.03%]
ABCA1 R219K多态性与中国农村人群端粒长度的相关性：可能与全身性炎症相关
Shutan Liao,Qing Zhou,Yang Zhang
Shutan Liao
The ATP-binding cassette transporter A1 (ABCA1) gene polymorphisms have been shown to be associated with various human diseases and pathological conditions such as cardiovascular disease and Alzheimer's disease. However, these associations ...
Mitochondrial markers differentiate two distinct phylogenetic groups in indigenous rice landraces of northeast India: an evolutionary insight [0.03%]
线粒体标记区分东北印度栽培稻地方品种中的两个谱系群：基于进化视角的见解
Madhuchhanda Parida,Gayatri Gouda,Parameswaran Chidambaranathan et al.
Madhuchhanda Parida et al.
The inheritance of the mitochondria genome and its diversity is unique for genetic and evolutionary studies relative to nuclear genomes. Northeast India and Himalayan regions are considered as one of the centres of indica rice origin. Also,...
Distinct gene expression patterns of SOX2 and SOX2OT variants in different types of brain tumours [0.03%]
SOX2和SOX2OT的不同变异在不同类型脑肿瘤中表达模式不同
Youssef Fouani,Akram Gholipour,Maziar Oveisee et al.
Youssef Fouani et al.
Numerous investigations have been recently published on the dysregulated expression of long-noncoding RNAs (lncRNAs) in various cancer types, emphasizing that abnormal lncRNA expression is a major contributor to tumourigenesis. A broad spec...
Intronic OTOF mutation causes an atypical splicing defect resulting in auditory neuropathy spectrum disorder [0.03%]
OTOF内含子突变导致非典型剪接缺陷并引起听力神经病谱系疾病
Sanaz Mohammadi,Hossein Jafari Khamirani,Sina Zoghi et al.
Sanaz Mohammadi et al.
Pathogenic variants in OTOF cause auditory neuropathy spectrum disorder (ANSD), namely prelingual nonsyndromic ANSD and temperature-sensitive ANSD (TS-ANSD). All study subjects provided blood sample for genetic analysis and sequencing. Whol...
Differential expression of the androgen receptor gene is correlated with CAG polymorphic repeats in patients with prostate cancer [0.03%]
前列腺癌患者中雄激素受体基因的差异表达与CAG多态性重复序列相关
MartíN Irigoyen Arredondo,José Romero Quintana,Eliakym Arámbula Meraz et al.
MartíN Irigoyen Arredondo et al.
Prostate cancer (PCa) is one of the most common types of cancer in men. The aetiology of the disease is not well established, but it has been related to one of the main pathways of regulation of prostate proliferation, mediated by androgens...
Transcribed intergenic regions exhibit a lower frequency of nucleotide polymorphism than the untranscribed intergenic regions in the genomes of Escherichia coli and Salmonella enterica [0.03%]
转录的基因间隔序列的单核苷酸多态性的频率低于非转录的基因间隔序列：来自大肠杆菌和沙门氏菌基因组的证据
Pratyush Kumar Beura,Piyali Sen,Ruksana Aziz et al.
Pratyush Kumar Beura et al.
The temporary exposure of single-stranded regions in the genome during the process of replication and transcription makes the region vulnerable to cytosine deamination resulting in a higher rate of C→T transition. Intraoperon intergenic re...
Identification of genetic polymorphism of the MBL2 gene and its association with clinical mastitis in Murrah buffaloes [0.03%]
MBL2基因多态性鉴定及其与摩拉水牛临床型乳腺炎的关联分析
Shahid Ahmad Shergojry,Archana Verma,Minerva Ghani et al.
Shahid Ahmad Shergojry et al.
Mastitis is a serious bovine disease which causes significant commercial loss. Polymorphism of mannose-binding lectin genes in bovine may be regarded as a functional and positional candidate gene for mastitis resistance and complement activ...
Many OX PHOS and replication factor mRNAs target mitochondria through specific binding to the organelle surface, independent of cotranslational protein import [0.03%]
许多OXPHOS和复制因子mRNA通过与细胞器表面的特异性结合将自身靶向到线粒体，独立于共翻译蛋白导入
Samit Adhya,Milon Banik
Samit Adhya
A large number of nucleus-encoded messenger RNAs (mRNAs) encoding proteins involved in oxidative phosphorylation have been found to be associated with mitochondria in vivo, indicating organelle-specific mRNA targeting. However, the identifi...