Magnetic Resonance Elastography for the Clinical Risk Assessment of Fibrosis, Cirrhosis, and Portal Hypertension in Patients With NAFLD [0.03%]
磁共振弹性成像技术用于评估非酒精性脂肪肝病患者的纤维化、肝硬化和门脉高压的临床风险
Yamini Natarajan,Rohit Loomba
Yamini Natarajan
Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming one of the most common causes of liver disease. The progressive subtype of NAFLD, nonalcoholic steatohepatitis (NASH), leads to cirrhosis, hepatocellular carcinoma, and mortality....
Naba Farooqui,Anshuman Elhence,Shalimar
Naba Farooqui
Chronic liver disease (CLD) is one of the leading causes of disability-adjusted life years in many countries. A recent understanding of nuclear bile acid receptor pathways has increased focus on the impact of crosstalk between the gut, bile...
Should We Treat Immune Tolerant Chronic Hepatitis B? Lessons from Asia [0.03%]
免疫耐受状态的慢性乙肝应该治疗吗？亚洲的经验
Madhumita Premkumar,Yogesh K Chawla
Madhumita Premkumar
Background: Chronic hepatitis B (CHB) remains a public health burden, with more than 257 million persons living with hepatitis B virus globally. Despite the availability of a safe and efficacious vaccine, access to immuni...
Portal Cavernoma Cholangiopathy in Children: An Evaluation Using Magnetic Resonance Cholangiography and Endoscopic Ultrasound [0.03%]
儿童先天性胆管血管瘤病的磁共振胆道造影和内镜超声评价
Vybhav Venkatesh,Surinder S Rana,Anmol Bhatia et al.
Vybhav Venkatesh et al.
Background: Portal cavernoma cholangiopathy (PCC) refers to abnormalities of the extra- and intrahepatic bile ducts in patients with portal cavernoma. The literature on PCC in children is very scarce. This study aimed at ...
Endoscopic Stone Extraction followed by Laparoscopic Cholecystectomy in Tandem for Concomitant Cholelithiasis and Choledocholithiasis: A Prospective Study [0.03%]
内镜取石后联合腹腔镜胆囊切除术治疗胆囊结石合并胆总管结石的前瞻性研究
Doraiswami Babu Vinish,Gautham Krishnamurthy,Patta Radhakrishna et al.
Doraiswami Babu Vinish et al.
Background: Single-session endoscopic stone extraction (ESE) and laparoscopic cholecystectomy (LC) has the best outcome in managing concomitant cholelithiasis (gallstone disease [GSD]) and choledocholithiasis (common bile...
Prevalence, Predictors, and Outcomes of Esophageal Candid iasis in Cirrhosis: An Observational Study With Systematic Re view and Meta-Analysis (CANDID-VIEW) [0.03%]
一项观察性研究及其系统评价和meta分析的结果：门脉高压症患者中食管念珠菌感染的流行率、预测因素及预后（CANDID-VIEW研究）
Nipun Verma,Saurabh Mishra,Shreya Singh et al.
Nipun Verma et al.
Background: Gastrointestinal candidiasis is often neglected and potentially serious infection in cirrhosis patients. Therefore, we evaluated the prevalence, risk factors, and outcomes of esophageal candidiasis (EC) in cir...
Diagnosis of Primary Sclerosing Cholangitis Beyond Childhood is Associated with Worse Outcomes [0.03%]
成人时期诊断原发性硬化性胆管炎与不良预后有关
Stefani Tica,Saad Alghamdi,Christopher Tait et al.
Stefani Tica et al.
Background: The elucidation of differences between adult and pediatric-onset primary sclerosing cholangitis (PSC) may inform clinical decision making, and whether results of adult PSC clinical trials can be extrapolated t...
Early Allograft Dysfunction After Live Donor Liver Transplantation: It's Time to Redefine? [0.03%]
活体肝移植后的早期移植物功能障碍：是重新定义的时候了吗？
Viniyendra Pamecha,Bramhadatta Pattnaik,Piyush K Sinha et al.
Viniyendra Pamecha et al.
Background: An ideal definition of early allograft dysfunction (EAD) after live donor liver transplantation (LDLT) remains elusive. The aim of the present study was to compare the diagnostic accuracies of existing EAD def...
Acute Variceal Bleed in Cirrhosis is Associated With Reversible Changes in Tight Junction Protein Expression in the Intestine: A Proof-of-Concept Study [0.03%]
肝硬化急性静脉曲张出血与肠道紧密连接蛋白表达的可逆改变有关：概念验证研究
Kanav Kaushal,Vipin Gupta,Pooja Goswami et al.
Kanav Kaushal et al.
Background: Tight junction proteins (TJPs) play an important role in gut-barrier dysfunction in cirrhosis and its complications such as acute variceal bleed (AVB). However, the dynamics of TJPs expression after AVB, its r...
Safety Assessment of Autologous Stem Cell Combination Therapy in Patients With Decompensated Liver Cirrhosis: A Pilot Study [0.03%]
自体干细胞联合治疗失代偿期肝硬化的安全性评估：一项试点研究
Mithun Sharma,Pavan K Pondugala,Shashidhar Jaggaihgari et al.
Mithun Sharma et al.
Background: Haematopoietic stem cell (HSC) infusion has demonstrated short-term improvement in liver functions in patients with chronic liver disease. The combination of HSC with mesenchymal stem cells (MSCs), which has a...