Cyto-genotoxicity Assessment of Potential Anti-tubercular Drug Candidate Molecule-trans-cyclohexane-1, 4-diamine Derivative-9u in Human Lung Epithelial Cells A549 [0.03%]
反结核药物候选分子反式环己烷-1,4-二胺衍生物-9u的细胞遗传毒性评估
Ekta Kapoor,Vinay Tripathi,Vivek Kumar et al.
Ekta Kapoor et al.
Increasing incidences of multiple drug-resistance (MDR) in Mycobacterium tuberculosis are emerging as one among the serious public health threats and socio-economic burden to the third world countries including India. Last couples of decade...
Serological changes induced by blend of sunset yellow, metanil yellow and tartrazine in swiss albino rat, rattus norvegicus [0.03%]
落日红、甲基橙和酒石黄混合物对瑞士小白鼠血液生化指标的影响研究
Beenam Saxena,Shiv Sharma
Beenam Saxena
Objective: The present study was carried out to evaluate the toxic effect of blend of some food colors on Swiss albino rats. Materials and methods: ...
Time-Dependent Regulation of Apoptosis by AEN and BAX in Response to 2-Aminoanthracene Dietary Consumption [0.03%]
膳食摄入2-氨基蒽引起的AEN和BAX对凋亡的时依赖性调节作用
Worlanyo Eric Gato,Stacey R McGee,Dale B Hales et al.
Worlanyo Eric Gato et al.
Background/objective: The modulation of the toxic effects of 2-aminoanthracene (2AA) on the liver by apoptosis was investigated. Fisher-344 (F344) rats were exposed to various concentrations of 2AA for 14 and 28 days. The...
Assessment of Toxicity of Monocrotophos in Freshwater Bivalve, Lamellidens marginalis, Using Different Markers [0.03%]
基于不同毒性指标的灭害威对淡水无脊椎生物瓦氏松脂扇贝壳的毒性评估研究
Anju Y Mundhe,Sangeeta V Pandit
Anju Y Mundhe
The present study was undertaken to evaluate the toxic effects of monocrotophos, a widely used organophosphorus pesticide, on Lamellidens marginalis with a wide battery of biomarkers consisting of AchE inhibition, lipid peroxidation, the le...
28-homobrassinolide alters protein content and activities of glutathione-s-transferase and polyphenol oxidase in raphanus sativus L. Plants under heavy metal stress [0.03%]
28-同环 brassinosteroid 调节芸苔素对重金属胁迫下萝卜生长和酶活性的影响
Neha Sharma,Gurjinder Singh Hundal,Indu Sharma et al.
Neha Sharma et al.
Objectives: The application of brassinosteroids (BRs), the plant steroidal hormones, results in an increased tolerance toward stress and thus helps improving the yield of crop plants. The present study was carried out to ...
Protective Assessment of Euphorbia neriifolia and its Isolated Flavonoid Against N-nitrosodiethylamine-induced Hepatic Carcinogenesis in Male Mice: A Histopathological Analysis [0.03%]
Euphorbia neriifolia及其分离黄酮类化合物对抗N-亚硝基二乙胺诱导的雄性小鼠肝癌发生保护作用的评价：病理组织学分析
Veena Sharma,Pracheta Janmeda
Veena Sharma
Aims: The aim of this study was to examine the impacts of N-nitrosodiethylamine (DENA), a potent environment carcinogen on liver tissue of mice which was attenuated by isolated flavonoid and hydro-ethanolic extract of Eup...
Ameliorative Effects of Operculina turpethum and its Isolated Stigma-5,22dien-3-o-β-D-glucopyranoside on the Hematological Parameters of Male Mice Exposed to N-Nitrosodimethylamine, a Potent Carcinogen [0.03%]
Operculina turpethum和其分离得到的光盘素-5,22dien-3-o-β-d-吡喃葡萄糖苷对N-亚硝基二甲胺诱导的小鼠血液学参数改善作用研究
Veena Sharma,Manu Singh
Veena Sharma
Objectives: Enormous propensity of plants to synthesize a variety of structurally diverse bioactive compounds, has made the plant kingdom a potential source of chemical constituents with various therapeutic values, includ...
Assessment of genotoxic potential of arsenic in female albino rats at permissible dose levels [0.03%]
砷在雌性白鼠中允许剂量水平的致突变潜力评估
Madhuri Mehta,Swarndeep Singh Hundal
Madhuri Mehta
Background: Arsenic is a wide spread environmental contaminant and has been recognized as a genotoxic element which is of major public health concern. Aim...
Tobacco dust induced genotoxicity as an occupational hazard in workers of bidi making cottage industry of central India [0.03%]
印度中央邦拜迪手工业工人职业危害的烟草尘致遗传毒性研究
Asha Khanna,Daya Shankar Gautam,Mamta Gokhale et al.
Asha Khanna et al.
Context: To explore genotoxicity in bidi rollers occupationally exposed to bidi tobacco dust. Aims: To assess the extent of genotoxicit...
Efficacy of crude extract of Emblica officinalis (amla) in arsenic-induced oxidative damage and apoptosis in splenocytes of mice [0.03%]
云香树提取物对小鼠脾细胞砷诱导的氧化损伤及凋亡的影响研究
Manish Kumar Singh,Suraj Singh Yadav,Rajesh Singh Yadav et al.
Manish Kumar Singh et al.
Introduction: Arsenic, an environmental contaminant naturally occurred in groundwater and has been found to be associated with immune-related health problems in humans. ...