Joint generalized estimating equations for multivariate longitudinal binary outcomes with missing data: An application to AIDS data [0.03%]
含缺失数据的多元纵向二分类结局资料的联合广义估计方程及其在艾滋病研究中的应用
Stuart R Lipsitz,Garrett M Fitzmaurice,Joseph G Ibrahim et al.
Stuart R Lipsitz et al.
In a large, prospective longitudinal study designed to monitor cardiac abnormalities in children born to HIV-infected women, instead of a single outcome variable, there are multiple binary outcomes (e.g., abnormal heart rate, abnormal blood...
Estimating stroke-free and total life expectancy in the presence of non-ignorable missing values [0.03%]
在不可忽略的缺失值存在下估计无卒中寿命和全部寿命期望值
Ardo van den Hout,Fiona E Matthews
Ardo van den Hout
A continuous time three-state model with time-dependent transition intensities is formulated to describe transitions between healthy and unhealthy states before death. By using time continuously, known death times can be taken into account....
Stuart G Baker,Nancy R Cook,Andrew Vickers et al.
Stuart G Baker et al.
Because many medical decisions are based on risk prediction models constructed from medical history and results of tests, the evaluation of these prediction models is important. This paper makes five contributions to this evaluation: (1) th...
Alleviating Linear Ecological Bias and Optimal Design with Sub-sample Data [0.03%]
缓解线性生态偏差和利用子样本数据进行最优设计
Adam Glynn,Jon Wakefield,Mark S Handcock et al.
Adam Glynn et al.
In this paper, we illustrate that combining ecological data with subsample data in situations in which a linear model is appropriate provides three main benefits. First, by including the individual level subsample data, the biases associate...
Cluster designs to assess the prevalence of acute malnutrition by lot quality assurance sampling: a validation study by computer simulation [0.03%]
通过计算机模拟验证急性营养不良发病情况的LOT质量保证抽样群聚设计：一项验证性研究
Casey Olives,Marcello Pagano,Megan Deitchler et al.
Casey Olives et al.
Traditional lot quality assurance sampling (LQAS) methods require simple random sampling to guarantee valid results. However, cluster sampling has been proposed to reduce the number of random starting points. This study uses simulations to ...
The use of simple reparameterizations to improve the efficiency of Markov chain Monte Carlo estimation for multilevel models with applications to discrete time survival models [0.03%]
利用简单的参数转换来提高多层模型的马尔可夫链蒙特卡洛估计效率及其在离散时间生存模型中的应用
William J Browne,Fiona Steele,Mousa Golalizadeh et al.
William J Browne et al.
We consider the application of Markov chain Monte Carlo (MCMC) estimation methods to random-effects models and in particular the family of discrete time survival models. Survival models can be used in many situations in the medical and soci...
Julian P T Higgins,Simon G Thompson,David J Spiegelhalter
Julian P T Higgins
Meta-analysis in the presence of unexplained heterogeneity is frequently undertaken by using a random-effects model, in which the effects underlying different studies are assumed to be drawn from a normal distribution. Here we discuss the j...
Accounting for uncertainty in health economic decision models by using model averaging [0.03%]
使用模型平均方法考虑健康经济决策模型中的不确定性
Christopher H Jackson,Simon G Thompson,Linda D Sharples
Christopher H Jackson
Health economic decision models are subject to considerable uncertainty, much of which arises from choices between several plausible model structures, e.g. choices of covariates in a regression model. Such structural uncertainty is rarely a...
Rebecca M Turner,David J Spiegelhalter,Gordon C S Smith et al.
Rebecca M Turner et al.
Policy decisions often require synthesis of evidence from multiple sources, and the source studies typically vary in rigour and in relevance to the target question. We present simple methods of allowing for differences in rigour (or lack of...
Hitting and missing targets by ambulance services for emergency calls: effects of different systems of performance measurement within the UK [0.03%]
救护服务体系对紧急呼救的响应：英国不同绩效评估体系的效果分析
Gwyn Bevan,Richard Hamblin
Gwyn Bevan
Following devolution, differences developed between UK countries in systems of measuring performance against a common target that ambulance services ought to respond to 75% of calls for what may be immediately life threatening emergencies (...