Silica nanoparticles as a delivery system for nucleic acid-based reagents [0.03%]
二氧化硅纳米微粒作为核酸试剂的载体系统
Christopher Hom,Jie Lu,Fuyuhiko Tamanoi
Christopher Hom
The transport of nucleic acid-based reagents is predicated upon developing structurally stable delivery systems that can preferentially bind and protect DNA and RNA, and release their cargo upon reaching their designated sites. Recent advan...
Functionalization of iron oxide nanoparticles with a versatile epoxy amine linker [0.03%]
利用多功能环氧胺连接体对铁氧化物纳米颗粒进行官能化处理
Michael Nickels,Jingping Xie,Jared Cobb et al.
Michael Nickels et al.
A synthetically diverse linker molecule consisting of both a terminal epoxide and a terminal amine has been synthesized and shown to have the desired reactivity. Proof of principle experimentation showed that the prepared linker molecule po...
Chen Fang,Miqin Zhang
Chen Fang
Magnetic nanoparticles (MNPs) have attracted enormous research attention due to their unique magnetic properties that enable the detection by the non-invasive medical imaging modality-magnetic resonance imaging (MRI). By incorporating advan...
Nanoparticle technology: Addressing the fundamental roadblocks to protein biomarker discovery [0.03%]
纳米粒子技术：解决蛋白质生物标志物发现的基本障碍
Alessandra Luchini,Caterina Longo,Virginia Espina et al.
Alessandra Luchini et al.
The incorporation of affinity baits into N-isopropylacrylamide-hydrogel-based nanoparticles offers a novel technology that addresses the major analytical challenges of disease biomarker discovery. In solution in complex biologic fluids (e.g...
Immobilization of magnetic iron oxide nanoparticles on laponite discs - an easy way to biocompatible ferrofluids and ferrogels [0.03%]
以拉卜石盘固定的磁性铁氧化物纳米颗粒-一种制备生物相容性铁流体和铁凝胶的简单方法
Vassilios Tzitzios,Georgia Basina,Aristides Bakandritsos et al.
Vassilios Tzitzios et al.
Magnetic nanocomposites containing iron oxide (maghemite) nanoparticles, well embedded in a synthetic clay matrix (laponite) were prepared by a new one step chemical route and characterized by TEM, XRD, magnetization measurements, Mössbaue...
A Novel Strategy for Surface Modification of Superparamagnetic Iron Oxide Nanoparticles for Lung Cancer Imaging [0.03%]
一种用于肺癌成像的超顺磁性铁 oxide 纳米颗粒表面改性的新策略
Gang Huang,Chunfu Zhang,Shunzi Li et al.
Gang Huang et al.
Superparamagnetic iron oxide (SPIO) nanoparticles are widely used in magnetic resonance imaging (MRI) as versatile ultra-sensitive nanoprobes for cellular and molecular imaging of cancer. In this study, we report a one-step procedure for th...
2,1,3-Benzothiadiazole (BTD)-moiety-containing red emitter conjugated amphiphilic poly(ethylene glycol)-block-poly(epsilon-caprolactone) copolymers for bioimaging [0.03%]
一种用于生物成像的含2,1,3-苯并噻二唑（BTD）基团的红色发射共轭两亲性聚乙二醇-嵌段-聚（ε-己内酯）共聚物
Yanqing Tian,Wen-Chung Wu,Ching-Yi Chen et al.
Yanqing Tian et al.
2,1,3-Benzothiadiazole (BTD)-containing red emitter was chemically conjugated onto amphiphilic poly(ethylene glycol)-block-poly(epsilon-caprolactone) (PEG-b-PCL) copolymers to form two new fluorophore-conjugated block copolymers (P5 and P7)...
Fabrication and functional characterization of goldnanoconjugates for potential application in ovarian cancer [0.03%]
卵巢癌应用前景的金纳米缀合物的制备及功能表征
Chitta Ranjan Patra,Resham Bhattacharya,Priyabrata Mukherjee
Chitta Ranjan Patra
In this paper we report the surface modification and functional characterization of a gold nanoparticle-based drug delivery system for potential therapeutic application in ovarian cancer. It is currently recognized that nanotechnology may p...
Synthesis and bio-functionalization of multifunctional magnetic Fe(3)O(4)@Y(2)O(3):Eu nanocomposites [0.03%]
多功能磁性Fe(3)O(4)@Y(2)O(3):Eu纳米复合材料的合成与生物功能化修饰
Zhi Ya Ma,Dosi Dosev,Mikaela Nichkova et al.
Zhi Ya Ma et al.
A facile homogenous precipitation method has been developed for the synthesis of multifunctional, magnetic, luminescent nanocomposites with Fe(3)O(4) nanoparticles as the core and europium-doped yttrium oxide (Y(2)O(3):Eu) as the shell. The...
Multifunctional Nanoparticles as Biocompatible Targeted Probes for Human Cancer Diagnosis and Therapy [0.03%]
多功能纳米颗粒作为生物相容性靶向探针用于人类癌症的诊断和治疗
Ken-Tye Yong,Indrajit Roy,Mark T Swihart et al.
Ken-Tye Yong et al.
The use of nanoparticles in biological application has been rapidly advancing toward practical applications in human cancer diagnosis and therapy. Upon linking the nanoparticles with biomolecules, they can be used to locate cancerous area a...