GABA and neuroligin signaling: linking synaptic activity and adhesion in inhibitory synapse development [0.03%]
GABA和神经鱼尼丁信号传导：连接抑制性突触发育中的突触活性与粘附作用
Z Josh Huang,Peter Scheiffele
Z Josh Huang
GABA-mediated synaptic inhibition is crucial in neural circuit operations. In mammalian brains, the development of inhibitory synapses and innervation patterns is often a prolonged postnatal process, regulated by neural activity. Emerging e...
Kathleen J Millen,Joseph G Gleeson
Kathleen J Millen
The molecular control of cell-type specification within the developing cerebellum as well as the genetic causes of the most common human developmental cerebellar disorders have long remained mysterious. Recent genetic lineage and loss-of-fu...
Robert J Johnston Jr,Claude Desplan
Robert J Johnston Jr
Though many neuronal cell fate decisions result in reproducible outcomes, stochastic choices often lead to spatial randomization of cell subtypes. This is often the case in sensory systems where expression of a specific sensory receptor gen...
The determination of projection neuron identity in the developing cerebral cortex [0.03%]
发育中的大脑皮层中投影神经元身份的决定
Dino P Leone,Karpagam Srinivasan,Bin Chen et al.
Dino P Leone et al.
Here we review the mechanisms that determine projection neuron identity during cortical development. Pyramidal neurons in the mammalian cerebral cortex can be classified into two major classes: corticocortical projection neurons, which are ...
Andrew C Lin,Christine E Holt
Andrew C Lin
An increasing body of evidence indicates that local axonal translation is required for growing axons to respond appropriately to guidance cues and other stimuli. Recent studies suggest that asymmetrical synthesis of cytoskeletal proteins me...
Frauke Drees,Frank B Gertler
Frauke Drees
The emergence of neurites from a symmetrical cell body is an essential feature of nervous system development. Neurites are the precursors of axons and dendrites and are tipped by growth cones, motile structures that guide elongating axons i...
Catherine Dulac,Tali Kimchi
Catherine Dulac
From invertebrates to humans, males and females of a given species display identifiable differences in behaviors, mostly but not exclusively pertaining to sexual and social behaviors. Within a species, individuals preferentially exhibit the...
Stuart N Baker
Stuart N Baker
Field potential recordings from motor cortex show oscillations in the beta-band (approximately 20 Hz), which are coherent with similar oscillations in the activity of contralateral contracting muscles. Recent findings have revised concepts ...
Neurobiology of behaviour [0.03%]
行为神经生物学
Barry J Dickson,Edvard I Moser
Barry J Dickson
W Otto Friesen,William B Kristan
W Otto Friesen
Research on the neuronal control of locomotion in leeches spans almost four decades. Recent advances reviewed here include discoveries that: (1) interactions between multiple hormones modulate initiation of swimming; (2) stretch receptors a...