G Nuñez,L del Peso
G Nuñez
The survival of cells in multicellular organisms requires continuous stimulation from the extracellular environment. The phosphatidylinositol-3' kinase/Akt signaling cascade has been identified as a critical pathway for the transduction of ...
D Kuhl,P Skehel
D Kuhl
The dendritic localization of mRNAs has been proposed to underlie the structural and functional polarity of neurons, as well as certain aspects of synaptic plasticity. Even though there is no conclusive evidence that such a localization is ...
L Shapiro,D R Colman
L Shapiro
The complex functions of the nervous system reflect the coordinated action of intricately connected networks of neurons. Recent work has combined to suggest the importance of the cadherin family of cell adhesion molecules in specifying thes...
Cajal-Retzius cells, Reelin, and the formation of layers [0.03%]
Cajal-Retzius细胞、Reelin与脑皮层板层结构的形成关系
M Frotscher
M Frotscher
Early-generated Cajal-Retzius cells in the marginal zone of the cortex synthesize and secrete the glycoprotein Reelin. The reelin gene is deleted in reeler mice, which show characteristic alterations in cortical lamination. Recent studies h...
J H Carson,S Kwon,E Barbarese
J H Carson
In the past year, several key molecular components of the RNA trafficking pathway in myelinating cells have been identified: distinct cis-acting elements for RNA transport and localization have been characterized in myelin basic protein mRN...
BEHAB/brevican: a brain-specific lectican implicated in gliomas and glial cell motility [0.03%]
BEHAB/ BREVICAN：一种脑特异性糖蛋白 神经胶质瘤和神经胶质细胞运动的候选基因
S C Gary,G M Kelly,S Hockfield
S C Gary
Several recent findings have advanced our understanding of the composition and function of the brain extracellular matrix (ECM). BEHAB/brevican, a recently identified CNS-specific proteoglycan, is a component of the brain ECM and is upregul...
Tracing axons [0.03%]
轴突追踪
C A Callahan,S Yoshikawa,J B Thomas
C A Callahan
For more than a century, neuroscientists have gained insight into brain function by examining its complex patterns of connectivity. To achieve this, a wide variety of axon-tracing techniques have been employed to chart the projections of ne...
M Goedert,M G Spillantini,S W Davies
M Goedert
Recent work has shown that abnormal filamentous inclusions within some nerve cells is a characteristic shared by Alzheimer's disease, some frontotemporal dementias, Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, as...
Sensory systems. Web alert [0.03%]
感觉系统。网络警报
J F Burke,P J Benson
J F Burke
Sensory systems [0.03%]
感觉系统
A J Hudspeth,K Tanaka
A J Hudspeth
Research on the senses spans the enormous range from analysis of individual molecules involved in sensory transduction to the attempted elucidation of conscious sensation. Because the variety of conceptual and experimental approaches varies...