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期刊名:Biospektrum

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ISSN:0947-0867

e-ISSN:1868-6249

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共收录本刊相关文章索引68条
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Florian Bourdeaux,Alexander Rittner,Martin Grininger Florian Bourdeaux
The Corona pandemic has painfully taught us the threat of new pathogens in a globalized world and how vital modern vaccines are. Platform technologies play an important role in the discovery of new vaccines as reducing the time for the deve...
Anna Fesser,Marcel Kaiser,Pascal Mäser Anna Fesser
Chagas disease is a zoonosis caused by Trypanosoma cruzi and transmitted by triatomine bugs. Autochthonous to Latin America, Chagas disease has spread globally through travel and migration. New drugs are needed urgently, in particular drugs...
Patrick Cramer,Goran Kokic,Christian Dienemann et al. Patrick Cramer et al.
Coronaviruses use an RNA-dependent RNA polymerase to replicate and transcribe their RNA genome. The structure of the SARS-CoV-2 polymerase was determined by cryo-electron microscopy within a short time in spring 2020. The structure explains...
Stefan Dübel,Andreas Herrmann,Thomas Schirrmann et al. Stefan Dübel et al.
COR-101 is a fully human, Fc silenced IgG that was discovered by antibody phage display. It reduced the SARS-CoV-2 virus load in the lung by more than 99 percent in Hamster models and led to much faster recovery. Its mode of action has been...
Kevin Klann,Christian Münch Kevin Klann
Upon infection with SARS-CoV-2, a variety of changes happen inside the host cell. The virus hijacks host cell pathways for driving its own replication, while the host counteracts with response mechanisms. To gain a comprehensive understandi...