Florian Bourdeaux,Alexander Rittner,Martin Grininger
Florian Bourdeaux
The Corona pandemic has painfully taught us the threat of new pathogens in a globalized world and how vital modern vaccines are. Platform technologies play an important role in the discovery of new vaccines as reducing the time for the deve...
Joachim L Schultze
Joachim L Schultze
Nina Scheurer,Daniela Kruck,Henning Hintzsche
Nina Scheurer
Anna Fesser,Marcel Kaiser,Pascal Mäser
Anna Fesser
Chagas disease is a zoonosis caused by Trypanosoma cruzi and transmitted by triatomine bugs. Autochthonous to Latin America, Chagas disease has spread globally through travel and migration. New drugs are needed urgently, in particular drugs...
Alexander J Westermann,Daniela Kruck,Henning Hintzsche
Alexander J Westermann
Patrick Cramer,Goran Kokic,Christian Dienemann et al.
Patrick Cramer et al.
Coronaviruses use an RNA-dependent RNA polymerase to replicate and transcribe their RNA genome. The structure of the SARS-CoV-2 polymerase was determined by cryo-electron microscopy within a short time in spring 2020. The structure explains...
Stefan Dübel,Andreas Herrmann,Thomas Schirrmann et al.
Stefan Dübel et al.
COR-101 is a fully human, Fc silenced IgG that was discovered by antibody phage display. It reduced the SARS-CoV-2 virus load in the lung by more than 99 percent in Hamster models and led to much faster recovery. Its mode of action has been...
Den molekularen Wirtszellveränderungen durch SARS-CoV-2 auf der Spur [0.03%]
追踪SARS-CoV-2引起的人体细胞变化分子特征
Kevin Klann,Christian Münch
Kevin Klann
Upon infection with SARS-CoV-2, a variety of changes happen inside the host cell. The virus hijacks host cell pathways for driving its own replication, while the host counteracts with response mechanisms. To gain a comprehensive understandi...
Daniela Kruck
Daniela Kruck
CRISPR-Cas: In Rekordzeit von der Grundlagenforschung zur Anwendung [0.03%]
CRISPR-Cas:从基础研究到应用的创纪录速度
Anita Marchfelder
Anita Marchfelder