Natalia Tschowri,Jochen Graw,Daniela Kruck et al.
Natalia Tschowri et al.
Journal Club [0.03%]
journal club期刊俱乐部
Jochen Graw,Harald Engelhardt,Kirsten Küsel et al.
Jochen Graw et al.
Atlas der SARS-CoV-2-RNA-Protein-Interaktionen in infizierten Zellen [0.03%]
SARS-CoV-2 RNA蛋白在感染细胞中的相互作用图集
Nora Schmidt,Mathias Munschauer
Nora Schmidt
Using RNA antisense purification and mass spectrometry, we identified more than 100 human proteins that directly and specifically bind SARS-CoV-2 RNA in infected cells. To gain insights into the functions of selected RNA interactors, we app...
Thomas Ulas,Anna C Aschenbrenner
Thomas Ulas
The COVID-19 pandemic is leading to increasing numbers of patients all over the world. Reports on a dysregulated immune system in the severe cases calls for a better characterization of the ongoing changes. To dissect COVID-19-driven immune...
Konstantin Sparrer,Frank Kirchhoff
Konstantin Sparrer
The Coronavirus disease 2019 (COVID-19) pandemic is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To facilitate its own replication and avoid immune control, SARS-CoV-2 manipulates its target cells. Our results...
Chiara Lichtenthaeler,Lasse Oberstrass,Julia E Weigand
Chiara Lichtenthaeler
Posttranscriptional regulation at mRNA level is defined not only by sequence, but also by the structure of the mRNA. Structures in the untranslated regions control stability, translation and localization of an mRNA. Evolutionary conservatio...
Gerald Haug
Gerald Haug
Martin Baunach,Jochen Graw,Henning Hintzsche
Martin Baunach
Journal Club [0.03%]
期刊俱乐部
Jochen Graw,Klaus Hantke,Wolfgang Wohlleben et al.
Jochen Graw et al.
SARS-CoV-PLpro-Inhibitoren als mögliche Breitspektrum-Virostatika [0.03%]
SARS-CoV-PLpro抑制剂作为可能的广谱抗病毒药物
Stefan Josef Hammerschmidt,Patrick Müller,Tanja Schirmeister
Stefan Josef Hammerschmidt
The SARS-CoV-encoded papain-like cysteine protease (PLpro) plays crucial roles in viral replication and maturation processes. It is required to cleave the precursor polyproteins into functional proteins. Thus, it is considered to be a promi...