High Density Lipoprotein Nanoparticles Deliver RNAi to Endothelial Cells to Inhibit Angiogenesis [0.03%]
高密度脂蛋白纳米颗粒向内皮细胞递送RNA干扰抑制血管生成
Sushant Tripathy,Elena Vinokour,Kaylin M McMahon et al.
Sushant Tripathy et al.
Systemic delivery of therapeutic nucleic acids to target cells and tissues outside of the liver remains a major challenge. We synthesized a biomimetic high density lipoprotein nanoparticle (HDL NP) for delivery of a cholesteryl modified the...
pH-Responsive Theranostic Polymer-Caged Nanobins (PCNs): Enhanced Cytotoxicity and T1 MRI Contrast by Her2-Targeting [0.03%]
PH响应性治疗诊断共聚物包封的纳米箱(PCN)：通过Her2靶向增强细胞毒性和T1 MRI对比度
Bong Jin Hong,Elden P Swindell,Keith W Macrenaris et al.
Bong Jin Hong et al.
A PCN theranostic platform comprises a doxorubicin (DXR)-loaded liposomal core and an acid-sensitive polymer shell that is functionalized with Herceptin and GdIII-based MRI contrast agents. In vitro testing reveals a 14-fold increase in DXR...
Oxidation Kinetics and Magnetic Properties of Elemental Iron Nanoparticles [0.03%]
元素铁纳米颗粒的氧化动力学及其磁性研究
Tae-Jong Yoon,Huilin Shao,Ralph Weissleder et al.
Tae-Jong Yoon et al.
Anti-CRLF2 Antibody-Armored Biodegradable Nanoparticles for Childhood B-ALL [0.03%]
负载抗CRLF2抗体的可降解纳米颗粒用于治疗儿童B细胞急性淋巴细胞白血病
Rekha Raghunathan,Swetha Mahesula,Kranthi Kancharla et al.
Rekha Raghunathan et al.
B-precursor acute lymphoblastic leukemia (B-ALL) lymphoblast (blast) internalization of anti-cytokine receptor-like factor 2 (CRLF2) antibody-armored biodegradable nanoparticles (AbBNPs) are investigated. First, AbBNPsaere synthesized by ad...