Mosaic Interdigitated Structure in Nanoparticle-Templated Phospholipid Bilayer Supports Partial Lipidation of Apolipoprotein A-I [0.03%]
纳米颗粒模板磷脂双层中的马赛克互指结构支持载脂蛋白A-I的部分脂化
Wangqiang Sun,Weiqiang Wu,Kaylin M McMahon et al.
Wangqiang Sun et al.
Using gold nanoparticle-templated high-density lipoprotein-like particles as a model, the nanoparticle-templated phospholipid bilayer is studied from the bottom-up. Data support the phospholipids have a mosaic interdigitated structure. The ...
A Multifunctional Nanocrystalline CaF2:Tm,Yb@mSiO2 System for Dual-Triggered and Optically Monitored Doxorubicin Delivery [0.03%]
一种用于多西他塞释放的多功能纳米晶CaF2:Tm，Yb@mSiO2系统：双重触发和光学监测
Yangyang Li,Yurong Zhou,Tongxu Gu et al.
Yangyang Li et al.
Daunting challenges in investigating the controlled release of drugs in complicated intracellular microenvironments demand the development of stimuli-responsive drug delivery systems. Here, a nanoparticle system, CaF2:Tm,Yb@mSiO2, made of a...
Wujin Sun,Yue Lu,Zhen Gu
Wujin Sun
Proteins exhibiting anticancer activities, especially those capable of discriminately killing cancer cells, have attracted increasing interest in developing protein-based anticancer therapeutics. This progress report surveys recent advances...
Multifunctional Polymer-Coated Carbon Nanotubes for Safe Drug Delivery [0.03%]
用于安全药物输送的多功能聚合物包覆碳纳米管
Thomas L Moore,Joshua E Pitzer,Ramakrishna Podila et al.
Thomas L Moore et al.
Though progress in the use carbon nanotubes in medicine has been most encouraging for therapeutic and diagnostic applications, any translational success must involve overcoming the toxicological and surface functionalization challenges inhe...
A Biomimetic Core-Shell Platform for Miniaturized 3D Cell and Tissue Engineering [0.03%]
一种用于微型三维细胞和组织工程的仿生核壳平台
Pranay Agarwal,Jung Kyu Choi,Haishui Huang et al.
Pranay Agarwal et al.
This article describes a biomimetic core-shell platform with a collagen-based core and an alginate hydrogel shell for cell and tissue culture. With this system, chemical and physical properties of extracellular matrix (ECM) in the core micr...
Nanoparticles functionalized with collagenase exhibit improved tumor accumulation in a murine xenograft model [0.03%]
胶原酶修饰的纳米颗粒在人源肿瘤异种移植小鼠模型中显示出更好的瘤内蓄积效果
Surya Murty,Taylor Gilliland,Peter Qiao et al.
Surya Murty et al.
Nanoparticles have garnered widespread interest for both the imaging and treatment of cancer due to their unique and tunable pharmacokinetics and their ability to carry a high payload of diverse compounds. However, despite these favorable a...
Facile Fabrication of Spherical Nanoparticle-Tipped AFM Probes for Plasmonic Applications [0.03%]
用于等离子体应用的AFM探针尖端球形纳米颗粒的简便制造方法
Alan Sanders,Liwu Zhang,Richard W Bowman et al.
Alan Sanders et al.
Addressing Key Technical Aspects of Quantum Dot Probe Preparation for Bioassays [0.03%]
量子点生物探针制备的关键技术问题探讨
Pavel Zrazhevskiy,Shivang R Dave,Xiaohu Gao
Pavel Zrazhevskiy
Fluorescent semiconductor nanoparticles, or quantum dots, have become a promising platform for the engineering of biofunctional probes for a variety of biomedical applications, ranging from multicolor imaging to single-molecule tracking to ...
Peptide-Targeted Gold Nanoparticles for Photodynamic Therapy of Brain Cancer [0.03%]
用于脑癌光动力治疗的肽靶向黄金纳米粒子
Joseph D Meyers,Yu Cheng,Ann-Marie Broome et al.
Joseph D Meyers et al.
Targeted drug delivery using epidermal growth factor peptide-targeted gold nanoparticles (EGFpep-Au NPs) is investigated as a novel approach for delivery of photodynamic therapy (PDT) agents, specifically Pc 4, to cancer. In vitro studies o...
Mechanistic Study on the Reduction of SWCNT-induced Cytotoxicity by Albumin Coating [0.03%]
白蛋白涂层降低单壁碳纳米管细胞毒性的机理研究
Yang Liu,Lei Ren,Dong Yan et al.
Yang Liu et al.
Single walled carbon nanotubes (SWCNTs) are utilized in many areas, accompanied with the ever rising safety concerns. Coating the SWCNTs by serum albumin has shown promises in reduction of their cytotoxicity. The cause of toxicity reduction...