Ultrastructure and biophysics of acetylcholine release: central role of the mediatophore [0.03%]
乙酰胆碱释放的超微结构和生物物理特性：介导子的核心作用
Y Dunant,M Israël
Y Dunant
We would like to review here some of the acquisitions gained by recent work in our two laboratories. Our approaches and results were intermingled and complementary. Thus we found it appropriate, for clarity and intelligibility, to merge the...
N Nelson
N Nelson
Vacuolar H(+)-ATPase (V-ATPase) plays a key role in neurotransmission. It provides the energy for the uptake and storage of neurotransmitters in synaptic vesicles and granules. It also may play a role in the biogenesis of synaptic vesicles ...
Tyrosine hydroxylase regulation in neurotransmission and neuroplasticity [0.03%]
多巴胺能神经信号转导和神经可塑性中的酪氨酸羟化酶调控机制研究
C Icard-Liepkalns,S Berrard,N Faucon Biguet et al.
C Icard-Liepkalns et al.
The modulation of neurotransmitter synthesis is a fundamental mechanism influencing neurotransmission and neuronal plasticity during development. The regulation of the tyrosine hydroxylase (TH) has been used to elucidate specific adaptative...
Physiology and biochemistry of peptidergic cotransmission in Aplysia [0.03%]
关于海兔肽能神经元共释放的现象的生理和生化机制的研究
K R Weiss,V Brezina,E C Cropper et al.
K R Weiss et al.
The marine mollusc Aplysia, whose simple nervous system facilitates study of the neural basis of behavior, was used to investigate the role of peptidergic cotransmission in feeding behavior. Several novel modulatory neuropeptides were purif...
Scinderin and chromaffin cell actin network dynamics during neurotransmitter release [0.03%]
分泌蛋白scinderin和肾上腺素能神经元的色素细胞actin网络在递质释放过程中的动态变化机制研究
J M Trifaró,M L Vitale,A Rodríguez Del Castillo
J M Trifaró
It has been demonstrated that filamentous actin (F-A) is mainly localized in the cortical surface of the chromaffin cell. This F-A network acts as a barrier to the chromaffin granules impeding their contact with the plasma membrane. Stimula...
Calcium-dependent modulation of the facilitation of transmitter release at neuromuscular junctions of Drosophila [0.03%]
钙依赖的促进神经肌肉突触间递质释放的调节机制研究——以果蝇为例
A Mallart
A Mallart
The relationship between external Ca and twin pulse facilitation of transmitter release has been investigated in neuromuscular junctions of Drosophila larvae using external electrodes to record excitatory junctional currents (ejcs). The deg...
J Vautrin,A E Schaffner,B Fontas et al.
J Vautrin et al.
In 1952 Fatt and Katz recorded at a frog neuromuscular junction while stimulating the nerve and found "... that successive endplate potential responses varied in a step-like manner, corresponding to units of miniature endplate potentials" (...
Role of different types of Ca2+ channels and a reticulum-like Ca2+ pump in neurotransmitter release [0.03%]
不同种类的Ca2+通道和类似内质网的Ca2+泵在神经递质释放中的作用
P Fossier,G Baux,L Tauc
P Fossier
The factors controlling the Ca2+ concentration directly responsible for triggering acetylcholine (ACh) release were investigated at an identified neuro-neuronal synapse of the Aplysia buccal ganglion. The types of presynaptic voltage-gated ...
R S Zucker
R S Zucker
The mechanism of transmitter release by intracellular Ca has been explored by recording presynaptic Ca concentration ([Ca2+]i) with Ca-sensitive fluorescent dyes and by controlling [Ca2+]i with photosensitive Ca chelators. [Ca2+]i decays sl...
F Drago,M Grassi,A A Genazzani
F Drago
The hypothesis that the improvement of neurochemical changes involving the brain dopaminergic and cholinergic systems in aged rats may be related to the their capacity of coping with stress has been investigated by testing the effect of var...