Voltage-clamp measurement of visually-evoked conductances with whole-cell patch recordings in primary visual cortex [0.03%]
全细胞膜片钳记录初级视觉皮层视蛋白介导的光诱发离子电导变化
L Borg-Graham,C Monier,Y Frégnac
L Borg-Graham
Whole cell patch recordings have been realized in the primary visual cortex of the anesthetized and paralyzed cat, in order to better characterize input resistance and time constant of visual cortical cells in vivo. Measurements of conducta...
M J Friedlander,K Harsanyi,P Kara
M J Friedlander
Brief epochs of pairing of low frequency synaptic activation and postsynaptic depolarization, in vitro, in supragranular neurons of nature guinea-pig visual cortex lead to a transient (20-60 min) synaptic potentiation. The process is due to...
Role of metabotropic glutamate receptors in the cat's visual cortex during development [0.03%]
代谢型谷氨酸受体在猫视觉皮层发育中的作用
N W Daw,S N Reid
N W Daw
We have studied the effect of metabotropic glutamate receptors on the second messenger cAMP, and how it varies with age in light- and dark-reared cats; the overall level of the metabotropic glutamate receptors mGluR1, 2/3, and 5 during deve...
mGluR1 mutant mice as a tool to study calcium signalling and multiple innervation in the cerebellum [0.03%]
mGluR1突变小鼠在研究皮层小脑中的钙信号及多神经支配方面的作用
H Daniel,C Levenes,F Conquet et al.
H Daniel et al.
The present study reports that calcium signalling through voltage-gated calcium channels and release from internal stores is impaired in Purkinje cells of mutant mice lacking in GluR1 receptors and that the absence of these receptors also l...
A discussion of activity-dependent forms of synaptic weakening and their possible role in ocular dominance plasticity [0.03%]
关于活动依赖的突触削弱形式及其可能在眼优势可塑性中的作用的讨论
S M Dudek
S M Dudek
Activity-dependent synaptic weakening is likely to be involved in numerous types of developmentally regulated cortical plasticity. The possible roles of two models of synaptic weakening, homosynaptic- and heterosynaptic-long-term-depression...
M Scanziani,R A Nicoll,R C Malenka
M Scanziani
Heterosynaptic long-term depression (hetLTD) at one input can be induced by applying a conditioning stimulus to an adjacent set of synapses. In hippocampal CA1 pyramidal cells, our results suggest that hetLTD is triggered by an extracellula...
The involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experiments [0.03%]
基因靶向实验证实脑源性神经营养因子与海马长期增强作用之间的关系
M Korte,V Staiger,O Griesbeck et al.
M Korte et al.
Brain-derived neurotrophic factor (BDNF) is a member of the NGF gene family, which has been shown to influence the survival and differentiation of specific classes of neurons in vitro and in vivo. The possibility that neurotrophins are also...
Postsynaptic calcium and calcium-dependent processes in synaptic plasticity in the developing visual cortex [0.03%]
发育性视皮层突触可塑性的 postsynaptic 钙和钙依赖性过程
T Tsumoto,H Yasuda,M Fukuda et al.
T Tsumoto et al.
In this paper we describe some of the results obtained from recent experiments on mechanisms underlying long-term potentiation (LTP) and long-term depression (LTD) in the visual cortex of young rats. In particular, we focus on experiments w...
C J Shatz
C J Shatz
Neural connections in the adult central nervous system are highly precise. In the visual system, retinal ganglion cells send their axons to target neurons in the lateral geniculate nucleus (LGN) in such a way that axons originating from the...
Dynamics of functional connectivity in visual cortical networks: an overview [0.03%]
视觉皮层网络功能连接的动态变化：综述
Y Frégnac
Y Frégnac
The aim of the Royaumont Symposium was to review various dynamic aspects of adaptive changes in functional connectivity, expressed in cortical networks during development, learning, and possibly during recognition and cognitive processing. ...