Some aspects of the effects of PL-10.1.AK-15 on the gastrointestinal tract [0.03%]
PL-10.1.AK-15对胃肠道影响的若干方面研究
D Erceg,V N Simicevic,M Kolega et al.
D Erceg et al.
PL-10.1.AK-15 is an active fragment of a naturally occurring protein first isolated from human gastric juice. Among its other protective effects, PL-10.1.AK-15 has demonstrated a protective effect on the gastrointestinal tract. The aim of t...
S Seiwerth,P Sikiric,Z Grabarevic et al.
S Seiwerth et al.
The 15 amino acid agent BPC 157, showing a wide range of organoprotective action in different experimental models, was used in our experiments in order to establish its influence on different elements connected with the healing process. Ele...
O M Abdel-Salam,J Szolcsányi,G Mózsik
O M Abdel-Salam
Capsaicin, the pungent principle of hot pepper, because of its ability to excite and later defunctionalize a subset of primary afferent neurons, has been extensively used as a probe to elucidate the function of these sensory neurons in a nu...
The influence of BPC 157 on nitric oxide agonist and antagonist induced lesions in broiler chicks [0.03%]
BPC 157对硝基化合物受体激动剂和拮抗剂诱导的肉鸡损伤的影响
Z Grabarevic,M Tisljar,B Artukovic et al.
Z Grabarevic et al.
We describe the effects of nitric oxide (NO) agonists and antagonists and the influence of a novel organoprotective pentadecapeptide BPC 157, on the development of pulmonary hypertension syndrome and tissue lesions in chicks. Acute toxicity...
Role of nitric oxide in pathogenesis of gastric mucosal damage induced by compound 48/80 in rats [0.03%]
硝酸盐在复合物48/80所致大鼠胃粘膜损伤中的作用机制研究
T Yasuhiro,A Konaka,H Ukawa et al.
T Yasuhiro et al.
We examined the effects of various nitric oxide synthase (NOS) inhibitors on development of gastric lesions induced by compound 48/80 (48/80) in rats and investigated the roles of NO and inducible NOS (iNOS) in inflammatory gastric response...
Growth hormone and somatostatin interaction in the ulcerogenic effect of cysteamine in female rats [0.03%]
半胱胺致大鼠胃溃疡作用中生长激素与生长抑素的相互作用
F Drago,C Montoneri
F Drago
It is known that cysteamine's ulcerogenic effect depends, among others, on a depletion of somatostatin (SRIH). Since growth hormone (GH) affects the release of hypothalamic SRIH, we have studied the influence of GH and the GH-SRIH interacti...
Capsaicin-sensitive mechanisms in the modulation of rat colonic vascular permeability under physiological and pathological conditions [0.03%]
辣椒素敏感性机制在生理和病理条件下调节大鼠结肠血管通透性中的作用
Z Szepes,J Kiss,T Molnár et al.
Z Szepes et al.
Inflammatory bowel disease (IBD) causes a prolonged life-quality reduction of patients and high costs for health services. The aim of this study was to explore the possible involvement of peptidergic capsaicin-sensitive afferent nerves (CSN...
Pentadecapeptide BPC 157 positively affects both non-steroidal anti-inflammatory agent-induced gastrointestinal lesions and adjuvant arthritis in rats [0.03%]
十五肽BPC 157对非甾体抗炎药诱导的大鼠胃肠粘膜损伤及佐剂性关节炎的保护作用
P Sikiric,S Seiwerth,Z Grabarevic et al.
P Sikiric et al.
Besides a superior protection of the pentadecapeptide BPC 157 (an essential fragment of an organoprotective gastric juice peptide BPC) against different gastrointestinal and liver lesions, an acute anti-inflammatory and analgetic activity w...
Developmental factors modify stress ulcer incidence in a stress-susceptible rat strain [0.03%]
发育因素改变应力易感大鼠品系的应激性溃疡发生率
W P Paré,J Kluczynski
W P Paré
Our multifactor theory of stress ulcer assumes that environmental factors that operate during early growth stages influence the elaboration of stress ulcer in adult rats. The theory would predict that rats exposed to either neonatal handlin...
Comparative Study
Journal of physiology, Paris. 1997 May-Oct;91(3-5):105-11. DOI:10.1016/s0928-4257(97)89473-9 1997
Effect of rilmenidine injection into the paraventricular nucleus of the hypothalamus on the water intake induced by application of angiotensin II to the subfornical organ [0.03%]
注射到下丘脑视上核的利美尼丁对背侧视前区给药血管紧张素II引起饮水的影响
C A Arrais,W A Saad,L A Camargo et al.
C A Arrais et al.